ArticleSTAR protocols2021
Protein purification and crystallization of HLA-A∗02:01 in complex with SARS-CoV-2 peptides.
Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Gp8 mediates adsorption of bacteriophage vB_VpP_jzsmvpa to the host Vibrio parahaemolyticus.Antonie van Leeuwenhoek · 2026Article
- Method for Producing Recombinant Soluble T-Cell Receptors.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I.Discovery immunology · 2026Article
- Assessing CD8Clinical & translational immunology · 2026Article
- Method for Performing T Cell Receptor-Peptide-Human Leukocyte Antigen Co-complexation and Structural Analysis.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Article
- Molecular basis of potent antiviral HLA-C-restricted CD8Nature communications · 2025Article
- Characterisation of an influenza B virus-derived peptide presented by HLA-B*18:01.The Biochemical journal · 2025Article
- Transcriptomic profiling reveals SARS-CoV-2-infected humanized MHC mice recapitulate human post vaccination immune responses.Frontiers in cellular and infection microbiology · 2025Article
- A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites.Nature communications · 2024Article
- Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes.Clinical & translational immunology · 2024Article
- The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.Current research in structural biology · 2024Article
- Molecular insights into the HLA-B35 molecules' classification associated with HIV control.Immunology and cell biology · 2024Article
- mRNA vaccine against malaria tailored for liver-resident memory T cells.Nature immunology · 2023Article
- Article
- A common allele of HLA mediates asymptomatic SARS-CoV-2 infection.medRxiv : the preprint server for health sciences · 2022Article
- HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people.PLoS pathogens · 2022Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding T-cell responses requires identifying viral peptides presented by human leukocyte antigens (HLAs). X-ray crystallography can be used to visualize their presentation. This protocol describes the expression, purification, and crystallization of HLA-A∗02:01, one of the most frequent HLA in the global population in complex with peptides derived from the SARS-CoV-2 nucleocapsid protein. This protocol can be applied to different HLA class I molecules bound to other peptides. For complete details on the use and execution of this protocol, please refer to Szeto et al. (2021).
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