Evidence map›Paper›PMID 34124681›Full record

ReviewMaterials advances2021

Fluorescent labeling of biocompatible block copolymers: synthetic strategies and applications in bioimaging.

Sophie Bou, Andrey S Klymchenko, Mayeul Collot

Abstract readReview
In one paragraph

Review in Materials advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  3. Review
  4. Review
  5. Article
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  7. Article
  8. Sterically TunedACS applied materials & interfaces · 2024
    Article
  9. Article
  10. Study of PEG-ACS omega · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sophie BouLaboratoire de Bioimagerie et Pathologies, UMR 7021, CNRS/Université de Strasbourg 74 route du Rhin 67401 Illkirch-Graffenstaden France mayeul.collot@unistra.fr.
Andrey S KlymchenkoLaboratoire de Bioimagerie et Pathologies, UMR 7021, CNRS/Université de Strasbourg 74 route du Rhin 67401 Illkirch-Graffenstaden France mayeul.collot@unistra.fr.ORCID https://orcid.org/0000-0002-2423-830X
Mayeul CollotLaboratoire de Bioimagerie et Pathologies, UMR 7021, CNRS/Université de Strasbourg 74 route du Rhin 67401 Illkirch-Graffenstaden France mayeul.collot@unistra.fr.ORCID https://orcid.org/0000-0002-8673-1730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among biocompatible materials, block copolymers (BCPs) possess several advantages due to the control of their chemistry and the possibility of combining various blocks with defined properties. Consequently, BCPs drew considerable attention as biocompatible materials in the fields of drug delivery, medicine and bioimaging. Fluorescent labeling of BCPs quickly appeared to be a method of choice to image and track these materials in order to better understand the nature of their interactions with biological media. However, incorporating fluorescent markers (FM) into BCPs can appear tricky; we thus intend to help chemists in this endeavor by reviewing recent advances made in the last 10 years. With the choice of the FM being of prior importance, we first reviewed their photophysical properties and functionalities for optimal labeling and imaging. In the second part the different chemical approaches that have been used in the literature to fluorescently label BCPs have been reviewed. We also report and discuss relevant applications of fluorescent BCPs in bioimaging.

Identifiers

PMID34124681
PMCPMC8142673

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.