Evidence map›Paper›PMID 34124679›Full record

ArticleRSC medicinal chemistry2021

Introduction of a cyano group at the 2-position of an (

Shuai Tan, Elisabetta Groaz, Mark N Prichard, Raj Kalkeri, Roger Ptak, Piet Herdewijn

Open access · greenAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 5 countries.

Shuai TanKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium Piet.Herdewijn@kuleuven.be.
Elisabetta GroazKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium Piet.Herdewijn@kuleuven.be.ORCID https://orcid.org/0000-0002-8866-2265
Mark N PrichardDepartment of Paediatrics, University of Alabama at Birmingham Birmingham AL 35294-3412 USA.
Raj KalkeriDepartment of Infectious Disease Research, Drug Development, Southern Research Institute 431 Aviation Way Frederick Maryland 21701 USA.
Roger PtakDepartment of Infectious Disease Research, Drug Development, Southern Research Institute 431 Aviation Way Frederick Maryland 21701 USA.
Piet HerdewijnKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium Piet.Herdewijn@kuleuven.be.ORCID https://orcid.org/0000-0003-3589-8503
Rega Institute for Medical Research · BESouthern Research Institute · USUniversity of Alabama at Birmingham · USUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The substantial impact of acyclic nucleoside phosphonates (ANPs) on human medicine encourages the synthesis of new ANP analogues with a potentially differentiated antiviral spectrum. Herein, we demonstrate the functionalization of the 2-position of the (

Identifiers

PMID34124679
PMCPMC8152930
OpenAlexW3159487078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.