Evidence map›Paper›PMID 34124676›Full record

ArticleRSC medicinal chemistry2021

The modulatory role of sulfated and non-sulfated small molecule heparan sulfate-glycomimetics in endothelial dysfunction: absolute structural clarification, molecular docking and simulated dynamics, SAR analyses and ADMET studies.

Daniel M Gill, Ana Paula R Povinelli, Gabriel Zazeri, Sabrina A Shamir, Ayman M Mahmoud, Fiona L Wilkinson, M Yvonne Alexander, Marinonio L Cornelio, Alan M Jones

Open access · hybridAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Rearrangement of Arylsulfamates and Sulfates toMolecules (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Sulfation of Phenolic Acids: Chemoenzymatic vs. Chemical Synthesis.International journal of molecular sciences · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Daniel M GillSchool of Pharmacy, University of Birmingham Edgbaston B15 2TT UK a.m.jones.2@bham.ac.uk +44(0)121 414 7288.
Ana Paula R PovinelliSchool of Pharmacy, University of Birmingham Edgbaston B15 2TT UK a.m.jones.2@bham.ac.uk +44(0)121 414 7288.
Gabriel ZazeriSchool of Pharmacy, University of Birmingham Edgbaston B15 2TT UK a.m.jones.2@bham.ac.uk +44(0)121 414 7288.
Sabrina A ShamirDepartment of Natural Sciences, Manchester Metropolitan University M1 5GD UK.
Ayman M MahmoudPhysiology Division, Department of Zoology, Faculty of Science, Beni-Suef University Egypt.ORCID https://orcid.org/0000-0003-0279-6500
Fiona L WilkinsonCentre for Biomedicine, Manchester Metropolitan University M1 5GD UK.
M Yvonne AlexanderCentre for Biomedicine, Manchester Metropolitan University M1 5GD UK.
Marinonio L CornelioDepartamento de Física - IBILCE Rua Cristovão Colombo 2265 CEP 15054-000 São José do Rio Preto São Paulo Brazil.
Alan M JonesSchool of Pharmacy, University of Birmingham Edgbaston B15 2TT UK a.m.jones.2@bham.ac.uk +44(0)121 414 7288.ORCID https://orcid.org/0000-0002-3897-5626
University of Birmingham · GBManchester Metropolitan University · GBBeni-Suef University · EG

Funding

Wellcome Trust
6 · The paper itself

Abstract

The conceptual technology of small molecule glycomimetics, exemplified by compounds

Identifiers

PMID34124676
PMCPMC8152814
OpenAlexW3160782230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.