ArticleEClinicalMedicine2021
Population-level faecal metagenomic profiling as a tool to predict antimicrobial resistance in
Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Mind the governance gap: a one health scoping review of national AMR performance indicators.npj antimicrobials and resistance · 2026Article
- Article
- Embedding risk monitoring in infectious disease surveillance for timely and effective outbreak prevention and control.BMJ global health · 2025Review
- Faecal microbiota and cytokine profiles of rural Cambodian infants linked to diet and diarrhoeal episodes.NPJ biofilms and microbiomes · 2024Article
- A Pipeline for Constructing Reference Genomes for Large Cohort-Specific Metagenome Compression.Microorganisms · 2023Article
- What are the missing pieces needed to stop antibiotic resistance?Microbial biotechnology · 2023Review
- Antimicrobial Resistance Pattern and Empirical Antibiotic Treatments in Neonatal Sepsis: A Retrospective, Single-Center, 12-Year Study.Antibiotics (Basel, Switzerland) · 2023Article
- Machine learning applications on neonatal sepsis treatment: a scoping review.BMC infectious diseases · 2023Article
- Wastewater surveillance of antibiotic-resistant bacterial pathogens: A systematic review.Frontiers in microbiology · 2022Review
- Microbiome Studies from Saudi Arabia over the Last 10 Years: Achievements, Gaps, and Future Directions.Microorganisms · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 9 institutions in 5 countries.
Funding
Abstract
backgroundAntimicrobial resistance (AMR) in
methodsIn this exploratory study, a novel approach to population-level prediction of AMR in
findingsPopulation metagenomes comprised samples from 177, 157, and 156 individuals in Kenya, the UK, and Cambodia, respectively, collected between September 2014 and April 2016. Clinical data from independent populations included 910, 3356 and 197 bacterial isolates from blood/cerebrospinal fluid infections in Kenya, the UK and Cambodia, respectively (samples collected between January 2010 and May 2017).
interpretationWhilst our findings are exploratory and require validation, intermittent metagenomics of pooled samples could represent an effective approach for AMR surveillance and to predict population-level AMR in clinical isolates, complementary to ongoing development of laboratory infrastructures processing individual samples.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.