Evidence map›Paper›PMID 34124335›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2021

R869C mutation in molecular motor

Orly Goldstein, Mali Gana-Weisz, Tamara Shiner, Reut Attar, Yael Mordechai, Yedael Y Waldman, Anat Bar-Shira, Avner Thaler, Tanya Gurevich, Anat Mirelman and 2 more

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Genes · 2023
    Article
  4. R869C mutation in molecular motorAlzheimer's & dementia (Amsterdam, Netherlands) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Orly GoldsteinThe Genomic Research Laboratory for Neurodegeneration, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Mali Gana-WeiszThe Genomic Research Laboratory for Neurodegeneration, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Tamara ShinerCognitive Neurology Unit, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Reut AttarThe Genomic Research Laboratory for Neurodegeneration, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Yael MordechaiThe Genomic Research Laboratory for Neurodegeneration, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Yedael Y WaldmanNRGene Ltd. Ness-Ziona Israel.
Anat Bar-ShiraThe Genomic Research Laboratory for Neurodegeneration, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Avner ThalerMovement Disorders Unit, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Tanya GurevichMovement Disorders Unit, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Anat MirelmanMovement Disorders Unit, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Nir GiladiMovement Disorders Unit, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Avi Orr-UrtregerThe Genomic Research Laboratory for Neurodegeneration, Neurological Institute Tel Aviv Sourasky Medical Center Tel Aviv Israel.
Tel Aviv Sourasky Medical Center · ILTel Aviv University · ILIsrael Institute for Biological Research · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction the

methodsWhole-genome sequencing of 95 Ashkenazi-N370S-carriers affected with either DLB (n = 19) or PD (n = 76) was performed, and 564 genes related to dementia and PD analyzed.

resultsWe identified enrichment of linked alleles in DISCUSSION: Because

Indexed as

dementia with Lewy bodiesGBAKIF17Parkinson's diseaserisk allele

Identifiers

PMID34124335
PMCPMC8176903
OpenAlexW3166470935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.