Evidence map›Paper›PMID 34124042›Full record

ArticleFrontiers in cell and developmental biology2021

An Optical Coherence Tomography-Based Deep Learning Algorithm for Visual Acuity Prediction of Highly Myopic Eyes After Cataract Surgery.

Ling Wei, Wenwen He, Jinrui Wang, Keke Zhang, Yu Du, Jiao Qi, Jiaqi Meng, Xiaodi Qiu, Lei Cai, Qi Fan and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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  11. Advances in OCT Imaging in Myopia and Pathologic Myopia.Diagnostics (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Ling WeiDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Wenwen HeDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Jinrui WangVisionary Intelligence Ltd, Beijing, China.
Keke ZhangDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Yu DuDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Jiao QiDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Jiaqi MengDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Xiaodi QiuDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Lei CaiDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Qi FanDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Zhennan ZhaoDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Yating TangDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Shuang NiDepartment of Ophthalmology, Heping Eye Hospital, Shanghai, China.
Haike GuoDepartment of Ophthalmology, Heping Eye Hospital, Shanghai, China.
Yunxiao SongIllinois Computer Science, University of Illinois, Champaign, IL, United States.
Xixi HeVisionary Intelligence Ltd, Beijing, China.
Dayong DingVisionary Intelligence Ltd, Beijing, China.
Yi LuDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Xiangjia ZhuDepartment of Ophthalmology, Eye and ENT Hospital, Eye Institute, Fudan University, Shanghai, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNEye & ENT Hospital of Fudan University · CNFudan University · CNHe Eye Hospital · CNUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to complicated and variable fundus status of highly myopic eyes, their visual benefit from cataract surgery remains hard to be determined preoperatively. We therefore aimed to develop an optical coherence tomography (OCT)-based deep learning algorithms to predict the postoperative visual acuity of highly myopic eyes after cataract surgery. MATERIALS AND

methodsThe internal dataset consisted of 1,415 highly myopic eyes having cataract surgeries in our hospital. Another external dataset consisted of 161 highly myopic eyes from Heping Eye Hospital. Preoperative macular OCT images were set as the only feature. The best corrected visual acuity (BCVA) at 4 weeks after surgery was set as the ground truth. Five different deep learning algorithms, namely ResNet-18, ResNet-34, ResNet-50, ResNet-101, and Inception-v3, were used to develop the model aiming at predicting the postoperative BCVA, and an ensemble learning was further developed. The model was further evaluated in the internal and external test datasets.

resultsThe ensemble learning showed the lowest mean absolute error (MAE) of 0.1566 logMAR and the lowest root mean square error (RMSE) of 0.2433 logMAR in the validation dataset. Promising outcomes in the internal and external test datasets were revealed with MAEs of 0.1524 and 0.1602 logMAR and RMSEs of 0.2612 and 0.2020 logMAR, respectively. Considerable sensitivity and precision were achieved in the BCVA < 0.30 logMAR group, with 90.32 and 75.34% in the internal test dataset and 81.75 and 89.60% in the external test dataset, respectively. The percentages of the prediction errors within ± 0.30 logMAR were 89.01% in the internal and 88.82% in the external test dataset.

conclusionPromising prediction outcomes of postoperative BCVA were achieved by the novel OCT-trained deep learning model, which will be helpful for the surgical planning of highly myopic cataract patients.

Indexed as

cataracthigh myopiamachine learningoptical coherence tomographyvisual acuity

Identifiers

PMID34124042
PMCPMC8187805
OpenAlexW3165634772

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.