Evidence map›Paper›PMID 34123951›Full record

ArticleEuropean journal of case reports in internal medicine2021

Blood Culture-negative Endocarditis Caused by

Silke Knol, Rogier L Nijhuis, Felix Geeraedts, Gerard Cm Linssen

Open access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Mindful diagnostics in culture-negative endocarditis: early noninvasive diagnosis ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Silke KnolDepartment of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The Netherlands.
Rogier L NijhuisDepartment of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The Netherlands.
Felix GeeraedtsLaboratory Microbiology Twente Achterhoek (LabMicTA), Hengelo, The Netherlands.
Gerard Cm LinssenDepartment of Cardiology, Hospital Group Twente (ZGT), Almelo and Hengelo, The Netherlands.
Ziekenhuis Groep Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

case descriptionA 67-year-old man was admitted with progressive heart failure due to blood culture-negative endocarditis of the aortic valve. Urgent aortic valve replacement was needed. Polymerase chain reaction (PCR) testing of samples of the explanted aortic valve revealed

conclusionWhipple's endocarditis should be considered in patients with arthralgia and blood culture-negative endocarditis (BCNIE). LEARNING POINTS: Whipple's endocarditis should be considered in patients with symptoms of arthralgia and blood culture-negative endocarditis (BCNIE).Serum polymerase chain reaction is the main diagnostic test.Both physician awareness and multidisciplinary management by regional endocarditis teams are recommended strategies to provide optimal patient care.

Indexed as

blood culture-negative endocarditisTropheryma whippleiWhipple’s endocarditis

Identifiers

PMID34123951
PMCPMC8191359
OpenAlexW3163756491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.