Evidence map›Paper›PMID 34123939›Full record

ArticleEuropean journal of case reports in internal medicine2021

Diffuse Calcinosis from Total Thyroidectomy and Secondary Hypocalcaemia.

Filipa Leal, Luís Nogueira, Teresa Martins Mendes, Ana Silva Rocha, Dinis Sarmento, Francisco Pombo, Bárbara Silva

Open access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Bilateral Cerebral Calcifications in Secondary Fahr's Syndrome.Case reports in neurological medicine · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Filipa LealCentro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.
Luís NogueiraCentro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.
Teresa Martins MendesCentro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.
Ana Silva RochaCentro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.
Dinis SarmentoCentro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.
Francisco PomboCentro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.
Bárbara SilvaCentro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.
Centro Hospitalar do Tâmega e Sousa · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoparathyroidism is a rare endocrine disorder and its main cause is cervical surgery such as thyroidectomy. The incidence of hypoparathyroidism after total thyroidectomy varies, and is reported to be between 0.3 and 6.3%. In terms of brain imaging, hypoparathyroidism can cause calcification mainly of the basal ganglia, with other areas rarely affected. Concerning extracerebral calcification, few studies have investigated the prevalence of visceral calcifications. We describe a case of a woman with secondary hypocalcaemia who presented with a transient ischaemic attack (TIA) and the investigation revealed an extensive calcinosis of the brain and the vascular structures responsible for the event. LEARNING POINTS: Iatrogenic hypoparathyroidism with hypocalcaemia is an important complication of total thyroidectomy. Hypocalcaemia manifestations can vary from asymptomatic to life-threatening conditions.Hypoparathyroidism (with hypocalcaemia) can cause cerebral calcification mainly of basal ganglia, with other areas of the brain rarely affected.Extracerebral calcifications are under-studied.

Indexed as

brain calcinosis syndromecerebral calcificationsHypoparathyroidism

Identifiers

PMID34123939
PMCPMC8191350
OpenAlexW3165794383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.