Evidence map›Paper›PMID 34123875›Full record

ArticleFrontiers in cellular and infection microbiology2021

Rapamycin Improves the Response of Effector and Memory CD8

Barbara Ferri Moraschi, Isaú Henrique Noronha, Camila Pontes Ferreira, Leonardo M Cariste, Caroline B Monteiro, Priscila Denapoli, Talita Vrechi, Gustavo J S Pereira, Ricardo T Gazzinelli, Joseli Lannes-Vieira and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
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  6. Observational
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Barbara Ferri MoraschiMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Isaú Henrique NoronhaMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Camila Pontes FerreiraMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Leonardo M CaristeRecombinant Vaccines Laboratory, Department of Biosciences, Federal University of São Paulo, Santos, Brazil.
Caroline B MonteiroRecombinant Vaccines Laboratory, Department of Biosciences, Federal University of São Paulo, Santos, Brazil.
Priscila DenapoliMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Talita VrechiDepartment of Pharmacology, Federal University of São Paulo, (UNIFESP), São Paulo, Brazil.
Gustavo J S PereiraDepartment of Pharmacology, Federal University of São Paulo, (UNIFESP), São Paulo, Brazil.
Ricardo T GazzinelliRené Rachou Research Center, Fiocruz, Belo Horizonte, Brazil.
Joseli Lannes-VieiraLaboratoy of Biology of the Interactions, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Maurício M RodriguesMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Karina R BortoluciMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
José Ronnie C VasconcelosMolecular Immunology Laboratory, Center of Molecular and Cellular Therapy, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Universidade Federal de São Paulo · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deficiency in memory formation and increased immunosenescence are pivotal features of

Indexed as

Protozoan VaccinesTrypanosoma cruziAnimalsCD8-Positive T-LymphocytesMiceMice, Inbred C57BLSirolimusVaccinationProtozoan VaccinesSirolimusCD8+ T-cellseffector CD8+ T cellsmemory CD8+ T cellsmTORrapamycinTrypanosoma cruzivaccine

Identifiers

PMID34123875
PMCPMC8191465
OpenAlexW3165690057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.