Evidence map›Paper›PMID 34123757›Full record

ArticleRestorative dentistry & endodontics2021

Biological assessment of a new ready-to-use hydraulic sealer.

Francine Benetti, João Eduardo Gomes-Filho, India Olinta de Azevedo-Queiroz, Marina Carminatti, Letícia Citelli Conti, Alexandre Henrique Dos Reis-Prado, Sandra Helena Penha de Oliveira, Edilson Ervolino, Elói Dezan-Júnior, Luciano Tavares Angelo Cintra

Abstract read
In one paragraph

Article in Restorative dentistry & endodontics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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  6. AnBioinformation · 2024
    Article
  7. In vivo cytotoxicity analysis of bioceramic root canal sealers on zebrafish embryo.Journal of dental research, dental clinics, dental prospects · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francine BenettiDepartment of Restorative Dentistry, Universidade Federal de Minas Gerais (UFMG), School of Dentistry, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-5459-353X
João Eduardo Gomes-FilhoDepartment of Preventive and Restorative Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil.ORCID https://orcid.org/0000-0001-5994-2287
India Olinta de Azevedo-QueirozDepartment of Preventive and Restorative Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil.ORCID https://orcid.org/0000-0001-8214-0880
Marina CarminattiDepartment of Preventive and Restorative Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil.ORCID https://orcid.org/0000-0002-3553-5772
Letícia Citelli ContiDepartment of Preventive and Restorative Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil.ORCID https://orcid.org/0000-0001-9261-332X
Alexandre Henrique Dos Reis-PradoDepartment of Restorative Dentistry, Universidade Federal de Minas Gerais (UFMG), School of Dentistry, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-5866-7137
Sandra Helena Penha de OliveiraDepartment of Basic Science, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil.ORCID https://orcid.org/0000-0003-0805-1120
Edilson ErvolinoDepartment of Basic Science, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil.ORCID https://orcid.org/0000-0003-4859-0583
Elói Dezan-JúniorDepartment of Preventive and Restorative Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil.ORCID https://orcid.org/0000-0002-5699-6578
Luciano Tavares Angelo CintraDepartment of Preventive and Restorative Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil.ORCID https://orcid.org/0000-0003-2348-7846

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study compared the cytotoxicity, biocompatibility, and tenascin immunolabeling of a new ready-to-use hydraulic sealer (Bio-C Sealer) with MTA-Fillapex and white MTA-Angelus. MATERIALS AND

methodsL929 fibroblasts were cultivated and exposed to undiluted and diluted material extracts. Polyethylene tubes with or without (the control) the materials were implanted into the dorsa of rats. At 7 days and 30 days, the rats were euthanized, and the specimens were prepared for analysis; inflammation and immunolabeling were measured, and statistical analysis was performed (

resultsMTA-Fillapex exhibited greater cytotoxicity than the other materials at all time points (

conclusionsBio-C Sealer and white MTA-Angelus exhibited greater cytocompatibility than MTA-Fillapex; all materials displayed adequate biocompatibility and induced tenascin immunolabeling.

Indexed as

BiocompatibilityCytotoxicityHydraulic sealerMineral trioxide aggregateTenascin

Identifiers

PMID34123757
PMCPMC8170373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.