Evidence map›Paper›PMID 34123511›Full record

ArticleBiomedical optics express2021

Raman spectroscopy for guidance of vulvar cancer surgery: a pilot study.

Helena C van Doorn, Elisa M Barroso, Senada Koljenović, Patricia C Ewing-Graham, M Rosa N Soares, Nick J van de Berg, Tom C Bakker Schut, Gerwin J Puppels

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Helena C van DoornDepartment of Gynaecologic Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Elisa M BarrosoDepartment of Pathology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Senada KoljenovićDepartment of Pathology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Patricia C Ewing-GrahamDepartment of Pathology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
M Rosa N SoaresDepartment of Pathology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Nick J van de BergDepartment of Gynaecologic Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Tom C Bakker SchutDepartment of Dermatology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Gerwin J PuppelsDepartment of Dermatology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For vulvar squamous cell carcinoma (VSCC), the mainstay of treatment is surgical removal with tumour-free margins. Surgeons still operate without objective tools that provide margin-status. This study assesses Raman spectroscopy potentiality for distinguishing ex-vivo VSCC from healthy tissue in 11 patients. Grid-based Raman maps were obtained from processed spectra. Water content and C-H band ratio (2,910-2,966 cm

Identifiers

PMID34123511
PMCPMC8176800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.