Evidence map›Paper›PMID 34123510›Full record

ArticleBiomedical optics express2021

Volumetric tumor delineation and assessment of its early response to radiotherapy with optical coherence tomography.

Valentin Demidov, Natalia Demidova, Layla Pires, Olga Demidova, Costel Flueraru, Brian C Wilson, I Alex Vitkin

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Journal of biomedical optics · 2025
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  4. Assessment of photodynamic therapy efficacy againstJournal of biomedical optics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Valentin DemidovUniversity of Toronto, Faculty of Medicine, Department of Medical Biophysics, 101 College St., Toronto, M5G 1L7, Canada.
Natalia DemidovaUniversity of Toronto at Mississauga, Department of Mathematical and Computational Sciences, 3359 Mississauga Road, Mississauga, L5L1C6, Canada.ORCID https://orcid.org/0000-0002-6048-5316
Layla PiresUniversity Health Network, Princess Margaret Cancer Centre, 610 University Avenue, Toronto, M5G 2M9, Canada.
Olga DemidovaSeneca College, Department of Arts and Science, 1750 Finch Ave. East, Toronto, M2J 2X5, Canada.
Costel FlueraruNational Research Council Canada, Information Communication Technology, 1200 Montreal Road, Ottawa, K1A 0R6, Canada.
Brian C WilsonUniversity of Toronto, Faculty of Medicine, Department of Medical Biophysics, 101 College St., Toronto, M5G 1L7, Canada.
I Alex VitkinUniversity of Toronto, Faculty of Medicine, Department of Medical Biophysics, 101 College St., Toronto, M5G 1L7, Canada.
University Health Network · CANational Research Council Canada · CASeneca Polytechnic · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Texture analyses of optical coherence tomography (OCT) images have shown initial promise for differentiation of normal and tumor tissues. This work develops a fully automatic volumetric tumor delineation technique employing quantitative OCT image speckle analysis based on Gamma distribution fits. We test its performance

Identifiers

PMID34123510
PMCPMC8176804
OpenAlexW3147026690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.