Evidence map›Paper›PMID 34123502›Full record

ArticleBiomedical optics express2021

Deep learning provides high accuracy in automated chondrocyte viability assessment in articular cartilage using nonlinear optical microscopy.

Xun Chen, Yang Li, Nicole Wyman, Zheng Zhang, Hongming Fan, Michael Le, Steven Gannon, Chelsea Rose, Zhao Zhang, Jeremy Mercuri and 5 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xun ChenDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Yang LiDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.ORCID https://orcid.org/0000-0002-2413-7875
Nicole WymanDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Zheng ZhangDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Hongming FanDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Michael LeDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Steven GannonDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Chelsea RoseDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Zhao ZhangDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Jeremy MercuriDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Hai YaoDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Bruce GaoDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Shane WoolfDepartment of Orthopedic, Medical University of South Carolina, Charleston, SC 29425, USA.
Thierry PécotHollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.
Tong YeDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA.ORCID https://orcid.org/0000-0003-1017-6969

Funding

South Carolina IDeA Networks of Biomedical Research (SC INBRE V)P20GM103499 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI EDIE C GOLDSMITH · 2012 to 2026
$61.0M
Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI RAYMOND N. DUBOIS · 2009 to 2026
$42.7M
Tissue Structural and Neural Remodeling in Human Sacroiliac JointP20GM121342 · NIGMS · CLEMSON UNIVERSITY · PI Peng Chen · 2018 to 2026
$24.7M
NCI NIH HHS P30 CA138313NIGMS NIH HHS P20 GM103499NIGMS NIH HHS P20 GM121342
6 · The paper itself

Abstract

Chondrocyte viability is a crucial factor in evaluating cartilage health. Most cell viability assays rely on dyes and are not applicable for

Identifiers

PMID34123502
PMCPMC8176803

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.