Evidence map›Paper›PMID 34123446›Full record

ArticleCase reports in ophthalmological medicine2021

Tubulointerstitial Nephritis and Uveitis Syndrome: Case Series and Literature Review.

Beatriz Oliveira Lopes, Margarida Sena Brízido, Ana Cortesão Costa, Mário Raimundo, Margarida Maria Miranda, Susana Morais Pina

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in ophthalmological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Beatriz Oliveira LopesDepartment of Ophthalmology, Beatriz Ângelo Hospital, Loures, Portugal.ORCID https://orcid.org/0000-0002-9622-3692
Margarida Sena BrízidoDepartment of Ophthalmology, Beatriz Ângelo Hospital, Loures, Portugal.ORCID https://orcid.org/0000-0002-0852-2837
Ana Cortesão CostaDepartment of Nephrology, Beatriz Ângelo Hospital, Loures, Portugal.ORCID https://orcid.org/0000-0001-5526-3287
Mário RaimundoDepartment of Nephrology, Beatriz Ângelo Hospital, Loures, Portugal.ORCID https://orcid.org/0000-0001-8068-717X
Margarida Maria MirandaDepartment of Ophthalmology, Beatriz Ângelo Hospital, Loures, Portugal.ORCID https://orcid.org/0000-0002-1954-5575
Susana Morais PinaDepartment of Ophthalmology, Beatriz Ângelo Hospital, Loures, Portugal.ORCID https://orcid.org/0000-0001-6700-6368
Hospital Beatriz Ângelo · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tubulointerstitial nephritis and uveitis syndrome (TINU) is a rare oculorenal inflammatory entity with a probable autoimmune etiology. Interstitial nephritis may be asymptomatic and usually has a benign course with spontaneous resolution. Uveitis, instead, is classically anterior, bilateral, and nongranulomatous, but it can be unilateral and presents as posterior uveitis or panuveitis, sometimes with a chronic or recurrent evolution. The frequent time lag of ocular and renal manifestations makes this diagnosis particularly challenging. The authors describe four cases of this rare entity, two with tubulointerstitial nephritis preceding ocular manifestations and the remaining, instead, with uveitis preceding renal involvement. The therapeutic approach included systemic corticosteroids in all cases. The addition of immunosuppressive therapy was required in three patients to achieve uveitis control. TINU is probably an underrecognized entity and should always be considered in the differential diagnosis of a chronic or recurrent idiopathic uveitis, especially in young patients who may have mild and asymptomatic renal disease.

Identifiers

PMID34123446
PMCPMC8189795
OpenAlexW3167367385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.