Evidence map›Paper›PMID 34123427›Full record

ArticleMultiple sclerosis international2021

Speed but Not Smoothness of Gait Reacts to Rehabilitation in Multiple Sclerosis.

Philipp Gulde, Joachim Hermsdörfer, Peter Rieckmann

Registry-linked trialAbstract read
In one paragraph

Article in Multiple sclerosis international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05385731 (MUSCLE - Nordic and Free Walking in People With Multiple Sclerosis), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05385731 naunknown statusnot on this mapstarted 2022, after this paper: background citation

MUSCLE - Nordic and Free Walking in People With Multiple Sclerosis: Clinical-functional, Motor Control, and Gait Analysis Findings: a Randomized Controlled Multicentre Clinical Trials

TypeinterventionalSponsorLeonardo A. Peyré-TartarugaRan2022 to 2024Enrolled60ConditionsMultiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary ProgressiveArmsNordic Walking (NWG), Free Walking (FWG), Health Education (HEG)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Philipp GuldeCentre for Clinical Neuroplasticity Medical Park Loipl, Bischofswiesen, Germany.ORCID https://orcid.org/0000-0001-5436-3462
Joachim HermsdörferTechnical University of Munich, Munich, Germany.ORCID https://orcid.org/0000-0002-6843-4871
Peter RieckmannCentre for Clinical Neuroplasticity Medical Park Loipl, Bischofswiesen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImproved gait is one of the leading therapy goals in multiple sclerosis. A plethora of clinical timed trials and state-of-the-art technology-based approaches are available to assess gait performance.

objectivesTo examine what aspects of gait react to inpatient rehabilitation in MS and which parameters should be best assessed.

designIn this longitudinal study, we examined the performance of 76 patients with MS to shed further light on factors influencing gait, associations between tests, and the reaction to inpatient rehabilitation during an average time span of 16 d.

resultsAll gait parameters were strongly intercorrelated (all

conclusionsSince we were not able to observe improvements in smoothness of gait, we conclude that rehabilitation programs should be adapted to the patient's physiological capacities in order to allow for such improvements in smoothness of gait. Externally valid gait capacity (6MWT) could be predicted by a single walk for 10 s at natural pace.

Identifiers

PMID34123427
PMCPMC8192191

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.