Evidence map›Paper›PMID 34123388›Full record

ReviewNew microbes and new infections2021

Alleviation of halitosis by use of probiotics and their protective mechanisms in the oral cavity.

M Karbalaei, M Keikha, N M Kobyliak, Z Khatib Zadeh, B Yousefi, M Eslami

Open access · goldAbstract readReview
In one paragraph

Review in New microbes and new infections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Decoding the power of the microbiome in human health.Frontiers in cellular and infection microbiology · 2026
    Review
  13. Article
  14. Microorganisms · 2025
    Review
  15. Article
  16. Heat-KilledMicroorganisms · 2024
    Article
  17. Article
  18. Article
  19. Improvement of halitosis by probiotic bacteriumFrontiers in microbiology · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

M KarbalaeiDepartment of Microbiology and Virology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran.
M KeikhaDepartment of Microbiology and Virology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
N M KobyliakDepartment of Endocrinology, Bogomolets National Medical University, Kyiv, Ukraine.
Z Khatib ZadehSchool of Dentistry, Semnan University of Medical Sciences, Semnan, Iran.
B YousefiDepartment of Immunology, Semnan University of Medical Sciences, Semnan, Iran.
M EslamiDepartment of Bacteriology and Virology, Semnan University of Medical Sciences, Semnan, Iran.
Semnan University of Medical Sciences · IRBogomolets National Medical University · UAMashhad University of Medical Sciences · IRUniversity of Jiroft · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regarding the relation of halitosis with oral infections and its effects on social relations between humans, the present study investigated the positive effects of probiotics on prevention or treatment of halitosis. The causative agents of halitosis are volatile sulphur compounds (VSCs), and halitosis is divided into oral and non-oral types according to the source of the VSCs. H

Indexed as

Dental carieshalitosisperiodontal diseasesprobioticvolatile sulphur compounds

Identifiers

PMID34123388
PMCPMC8173312
OpenAlexW3157197717

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.