Construction of diverse peptide structural architectures

Carina Hey Pui Cheung, Jianchao Xu, Chi Lung Lee, Yanfeng Zhang, Ruohan Wei, Donald Bierer, Xuhui Huang, Xuechen Li

Open access · diamondAbstract read

In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.6field-weighted citation impact, top 36% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.RSC chemical biology · 2021
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Carina Hey Pui CheungDepartment of Chemistry, State Key Lab of Synthetic Chemistry, The University of Hong Kong Hong Kong xuechenl@hku.hk.

Jianchao XuDepartment of Chemistry, State Key Lab of Synthetic Chemistry, The University of Hong Kong Hong Kong xuechenl@hku.hk.

Chi Lung LeeDepartment of Chemistry, State Key Lab of Synthetic Chemistry, The University of Hong Kong Hong Kong xuechenl@hku.hk.ORCID https://orcid.org/0000-0001-8500-6572

Yanfeng ZhangDepartment of Chemistry, State Key Lab of Synthetic Chemistry, The University of Hong Kong Hong Kong xuechenl@hku.hk.

Ruohan WeiDepartment of Chemistry, State Key Lab of Synthetic Chemistry, The University of Hong Kong Hong Kong xuechenl@hku.hk.

Donald BiererDepartment of Medicinal Chemistry, Bayer AG Aprather Weg 18A 42096 Wuppertal Germany.

Xuhui HuangDepartment of Biological and Chemical Engineering, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong.ORCID https://orcid.org/0000-0002-7119-9358

Xuechen LiDepartment of Chemistry, State Key Lab of Synthetic Chemistry, The University of Hong Kong Hong Kong xuechenl@hku.hk.ORCID https://orcid.org/0000-0001-5465-7727

University of Hong Kong · HKHong Kong University of Science and Technology · HKUniversity of Wuppertal · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report the development of a facile synthetic strategy for constructing diverse peptide structural architectures

Identifiers

PMID34123337

DOI10.1039/d1sc01174j

PMCPMC8153220

OpenAlexW3153659289

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.