Evidence map›Paper›PMID 34123281›Full record

ArticleChemical science2020

Chemical tagging for sensitive determination of uridine modifications in RNA.

Qing-Yun Cheng, Jun Xiong, Cheng-Jie Ma, Yi Dai, Jiang-Hui Ding, Fei-Long Liu, Bi-Feng Yuan, Yu-Qi Feng

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Conserved 5-methyluridine tRNA modification modulates ribosome translocation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Machine learning-empoweredChemical science · 2023
    Article
  17. Transcriptome-wide profiling ofChemical science · 2022
    Article
  18. Article
  19. Opportunities and Challenges to Profile mRNA Modifications in Escherichia coli.Chembiochem : a European journal of chemical biology · 2022
    Article
  20. Genome-wide mapping ofChemical science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qing-Yun ChengKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Sauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 P.R. China bfyuan@whu.edu.cn +86-27-68755595 +86-27-68755595.
Jun XiongKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Sauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 P.R. China bfyuan@whu.edu.cn +86-27-68755595 +86-27-68755595.
Cheng-Jie MaKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Sauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 P.R. China bfyuan@whu.edu.cn +86-27-68755595 +86-27-68755595.
Yi DaiKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Sauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 P.R. China bfyuan@whu.edu.cn +86-27-68755595 +86-27-68755595.
Jiang-Hui DingKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Sauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 P.R. China bfyuan@whu.edu.cn +86-27-68755595 +86-27-68755595.
Fei-Long LiuKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Sauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 P.R. China bfyuan@whu.edu.cn +86-27-68755595 +86-27-68755595.
Bi-Feng YuanKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Sauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 P.R. China bfyuan@whu.edu.cn +86-27-68755595 +86-27-68755595.ORCID https://orcid.org/0000-0001-5223-4659
Yu-Qi FengKey Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Sauvage Center for Molecular Sciences, Department of Chemistry, Wuhan University Wuhan 430072 P.R. China bfyuan@whu.edu.cn +86-27-68755595 +86-27-68755595.ORCID https://orcid.org/0000-0003-1107-5385
Ministry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery of dynamic and reversible modifications in messenger RNA (mRNA) is opening new directions in RNA modification-mediated regulation of biological processes. Methylation is the most prevalent modification occurring in mRNA and the methyl group is mainly decorated in the adenine, cytosine, and guanine base or in the 2'-hydroxyl group of ribose. However, methylation of the uracil base (5-methyluridine, m

Identifiers

PMID34123281
PMCPMC8148390
OpenAlexW3000702336

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.