ArticleChemical science2019
Ultrafast spectral hole burning reveals the distinct chromophores in eumelanin and their common photoresponse.
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 63 citations in OpenAlex.
- Common Photoproperties of Eumelanin and Natural Organic Matter Emerge from Ensembles of Few-Layered Nanostructures.ACS central science · 2026Article
- Characterizing excited triplet states of synthetic eumelanin and pheomelanin by the application of selected diene probes.Scientific reports · 2026Article
- Allomelanin: A Promising Alternative to Polydopamine for Bioapplications.Journal of functional biomaterials · 2026Review
- From melanogenesis to melanin technologies.Communications chemistry · 2025Review
- Photothermal Release by Melanin-like Nanoparticles: Biomedical Applications.Journal of functional biomaterials · 2025Review
- Article
- Unexplored Mechanisms of Photoprotection: Synergistic Light Absorption and Antioxidant Activity of Melanin.Antioxidants (Basel, Switzerland) · 2025Review
- Photochemical Pathways and Light-Enhanced Radical Scavenging Activity of 1,8-Dihydroxynaphthalene Allomelanin.Journal of the American Chemical Society · 2025Article
- Physiological Roles of Eumelanin- and Melanogenesis-Associated Diseases: A Look at the Potentialities of Engineered and Microbial Eumelanin in Clinical Practice.Bioengineering (Basel, Switzerland) · 2024Review
- Melanin for Photoprotection and Hair Coloration in the Emerging Era of Nanocosmetics.International journal of molecular sciences · 2024Review
- Functionalization of and through Melanin: Strategies and Bio-Applications.International journal of molecular sciences · 2023Review
- Prominent Roles and Conflicted Attitudes of Eumelanin in the Living World.International journal of molecular sciences · 2023Review
- Chemiexcited Neurotransmitters and Hormones Create DNA Photoproducts in the Dark.ACS chemical biology · 2023Article
- Article
- Chemiexcitation: Mammalian Photochemistry in the DarkPhotochemistry and photobiology · 2023Review
- Structural analysis of melanosomes in living mammalian cells using scanning electron-assisted dielectric microscopy with deep neural network.Computational and structural biotechnology journal · 2023Article
- Reversible Supramolecular Noncovalent Self-Assembly Determines the Optical Properties and the Formation of Melanin-like Nanoparticles.The journal of physical chemistry letters · 2022Article
- The photoprotection mechanism in the black-brown pigment eumelanin.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Fingerprint-based deep neural networks can model thermodynamic and optical properties of eumelanin DHI dimers.Chemical science · 2022Article
- Exciton interactions in helical crystals of a hydrogen-bonded eumelanin monomer.Chemical science · 2022Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eumelanin, the brown-black pigment found in organisms from bacteria to humans, dissipates solar energy and prevents photochemical damage. While the structure of eumelanin is unclear, it is thought to consist of an extremely heterogeneous collection of chromophores that absorb from the UV to the infrared, additively producing its remarkably broad absorption spectrum. However, the chromophores responsible for absorption by eumelanin and their excited state decay pathways remain highly uncertain. Using femtosecond broadband transient absorption spectroscopy, we address the excited state behavior of chromophore subsets that make up a synthetic eumelanin, DOPA melanin, and probe the heterogeneity of its chromophores. Tuning the excitation light over more than an octave from the UV to the visible and probing with the broadest spectral window used to study any form of melanin to date enable the detection of spectral holes with a linewidth of 0.6 eV that track the excitation wavelength. Transient spectral hole burning is a manifestation of extreme chemical heterogeneity, yet exciting these diverse chromophores unexpectedly produces a common photoinduced absorption spectrum and similar kinetics. This common photoresponse is assigned to the ultrafast formation of immobile charge transfer excitons that decay locally and that are formed among graphene-like chromophores in less than 200 fs. Raman spectroscopy reveals that chromophore heterogeneity in DOPA melanin arises from different sized domains of sp
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