ArticleChemical science2020
A near-infrared fluorescence probe for imaging of pantetheinase in cells and mice
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- A Review of Detection Probes for Vanin-1: Development and Biological Applications in Various Inflammatory Diseases.Chemistry & biodiversity · 2026Pooled it
- Near-Infrared and Shortwave Infrared Building Blocks for Activity-Based Sensors in Animals.Bioconjugate chemistry · 2026Review
- Visual Identification ofAnalytical chemistry · 2022Article
- Near-infrared fluorescent probe for hydrogen sulfide: high-fidelity ferroptosis evaluationChemical science · 2022Article
- A NIR fluorescent probe for Vanin-1 and its applications in imaging, kidney injury diagnosis, and the development of inhibitor.Acta pharmaceutica Sinica. B · 2022Article
- Time-resolved analysis of photoluminescence at a single wavelength for ratiometric and multiplex biosensing and bioimaging.Chemical science · 2021Article
- Visualization-Based Discovery of Vanin-1 Inhibitors for Colitis.Frontiers in chemistry · 2021Article
- Lighting up Individual Organelles With Fluorescent Carbon Dots.Frontiers in chemistry · 2021Review
- Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging.Frontiers in chemistry · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pantetheinase is an amidohydrolase that cleaves pantetheine into pantothenic acid and cysteamine. Functional studies have found that ubiquitous expression of this enzyme is associated with many inflammatory diseases. However, the lack of near-infrared fluorescence probes limits the better understanding of the functions of the enzyme. In this work, we have developed a new near-infrared fluorescence probe, CYLP, for bioimaging of pantetheinase by using pantothenic acid with a self-immolative linker as a recognition group. The probe produces a sensitive fluorescence off-on response at 710 nm to pantetheinase with a detection limit of 0.02 ng mL
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.