ArticleChemical science2020
Template effects of vesicles in dynamic covalent chemistry.
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Coupling Photoresponsive Transmembrane Ion Transport with Transition Metal Catalysis.Journal of the American Chemical Society · 2024Article
- Chemical Information Processing by a Responsive Chemical System.Journal of the American Chemical Society · 2024Article
- Dynamic covalent synthesis.Chemical science · 2024Review
- Dynamic Covalent Michael Acceptors to Penetrate Cells: Thiol-Mediated Uptake with Tetrel-Centered Exchange Cascades, Assisted by Halogen-Bonding Switches.Angewandte Chemie (International ed. in English) · 2022Article
- Dynamic Hydroxyl-Yne Reaction with Phenols.Organic letters · 2022Article
- Artificial transmembrane signal transduction mediated by dynamic covalent chemistry.Chemical science · 2021Article
- Dithiolane quartets: thiol-mediated uptake enables cytosolic delivery in deep tissue.Chemical science · 2021Article
- Pnictogen-Bonding Catalysis and Transport Combined: Polyether Transporters Made In Situ.JACS Au · 2021Article
- Supramolecular chemistry in lipid bilayer membranes.Chemical science · 2021Review
- Dynamic Nucleophilic Aromatic Substitution of Tetrazines.Angewandte Chemie (International ed. in English) · 2021Article
- Thiol-Mediated Uptake.JACS Au · 2021Review
- Inhibitors of thiol-mediated uptake.Chemical science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vesicle lipid bilayers have been employed as templates to modulate the product distribution in a dynamic covalent library of Michael adducts formed by mixing a Michael acceptor with thiols. In methanol solution, all possible Michael adducts were obtained in similar amounts. Addition of vesicles to the dynamic covalent library led to the formation of a single major product. The equilibrium constants for formation of the Michael adducts are similar for all of the thiols used in this experiment, and the effect of the vesicles on the composition of the library is attributed to the differential partitioning of the library members between the lipid bilayer and the aqueous solution. The results provide a quantitative approach for exploiting dynamic covalent chemistry within lipid bilayers.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.