Evidence map›Paper›PMID 34123129›Full record

ArticleChemical science2020

Intracellular monitoring of NADH release from mitochondria using a single functionalized nanowire electrode.

Hong Jiang, Yu-Ting Qi, Wen-Tao Wu, Ming-Yong Wen, Yan-Ling Liu, Wei-Hua Huang

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hong JiangCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China whhuang@whu.edu.cn.
Yu-Ting QiCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China whhuang@whu.edu.cn.
Wen-Tao WuCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China whhuang@whu.edu.cn.
Ming-Yong WenCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China whhuang@whu.edu.cn.
Yan-Ling LiuCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China whhuang@whu.edu.cn.
Wei-Hua HuangCollege of Chemistry and Molecular Sciences, Wuhan University Wuhan 430072 China whhuang@whu.edu.cn.ORCID https://orcid.org/0000-0001-8951-075X
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are the powerhouse of cells, and also their suicidal weapon store. Mitochondrial dysfunction can cause the opening of the mitochondrial permeability transition pore (mPTP) and nicotinamide adenine dinucleotide (NADH) release from mitochondria, eventually leading to the disruption of energy metabolism and even cell death. Hence, NADH is often considered a marker of mitochondrial function, but

Identifiers

PMID34123129
PMCPMC8163350
OpenAlexW3047407470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.