Evidence map›Paper›PMID 34123110›Full record

ArticleChemical science2020

A ratiometric fluorescent probe for real-time monitoring of intracellular glutathione fluctuations in response to cisplatin.

Hanzhuang Liu, Wenting Song, Shuren Zhang, Kin Shing Chan, Zijian Guo, Zhen Shen

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
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  9. Photocatalytic Pt(IV)-Coordinated Carbon Dots for Precision Tumor Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hanzhuang LiuState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210046 China zguo@nju.edu.cn zshen@nju.edu.cn.ORCID https://orcid.org/0000-0003-3860-6967
Wenting SongState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210046 China zguo@nju.edu.cn zshen@nju.edu.cn.
Shuren ZhangState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210046 China zguo@nju.edu.cn zshen@nju.edu.cn.
Kin Shing ChanState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210046 China zguo@nju.edu.cn zshen@nju.edu.cn.
Zijian GuoState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210046 China zguo@nju.edu.cn zshen@nju.edu.cn.ORCID https://orcid.org/0000-0003-4986-9308
Zhen ShenState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University Nanjing 210046 China zguo@nju.edu.cn zshen@nju.edu.cn.ORCID https://orcid.org/0000-0003-2464-1278
Nanjing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Real-time imaging of fluctuations in intracellular glutathione (GSH) concentrations is critical to understanding the mechanism of GSH-related cisplatin-resistance. Here, we describe a ratiometric fluorescence probe based on a reversible Michael addition reaction of GSH with the vinyl-functionalized boron-dipyrromethene (4,4-difluoro-4-bora-3

Identifiers

PMID34123110
PMCPMC8163343
OpenAlexW3045794306

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.