Evidence map›Paper›PMID 34123103›Full record

ArticleChemical science2020

Simultaneously boosting the conjugation, brightness and solubility of organic fluorophores by using AIEgens.

Ji Qi, Xingchen Duan, Yuanjing Cai, Shaorui Jia, Chao Chen, Zheng Zhao, Ying Li, Hui-Qing Peng, Ryan T K Kwok, Jacky W Y Lam and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ji QiDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China tangbenz@ust.hk.
Xingchen DuanState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education and College of Life Sciences, Nankai University Tianjin 300071 China dingd@nankai.edu.cn.
Yuanjing CaiBeijing Advanced Innovation Centre for Soft Matter Science and Engineering, Beijing University of Chemical Technology Beijing 100029 China.ORCID https://orcid.org/0000-0002-3758-7277
Shaorui JiaDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China tangbenz@ust.hk.
Chao ChenState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education and College of Life Sciences, Nankai University Tianjin 300071 China dingd@nankai.edu.cn.
Zheng ZhaoDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China tangbenz@ust.hk.ORCID https://orcid.org/0000-0002-5536-0439
Ying LiDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China tangbenz@ust.hk.
Hui-Qing PengDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China tangbenz@ust.hk.
Ryan T K KwokDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China tangbenz@ust.hk.
Jacky W Y LamDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China tangbenz@ust.hk.
Dan DingState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education and College of Life Sciences, Nankai University Tianjin 300071 China dingd@nankai.edu.cn.ORCID https://orcid.org/0000-0003-1873-6510
Ben Zhong TangDepartment of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China tangbenz@ust.hk.ORCID https://orcid.org/0000-0002-0293-964X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organic near-infrared (NIR) emitters hold great promise for biomedical applications. Yet, most organic NIR fluorophores face the limitations of short emission wavelengths, low brightness, unsatisfactory processability, and the aggregation-caused quenching effect. Therefore, development of effective molecular design strategies to improve these important properties at the same time is a highly pursued topic, but very challenging. Herein, aggregation-induced emission luminogens (AIEgens) are employed as substituents to simultaneously extend the conjugation length, boost the fluorescence quantum yield, and increase the solubility of organic NIR fluorophores, being favourable for biological applications. A series of donor-acceptor type compounds with different substituent groups (

Identifiers

PMID34123103
PMCPMC8163428

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.