Evidence map›Paper›PMID 34123091›Full record

ArticleChemical science2020

Rational design of an "all-in-one" phototheranostic.

Zi-Shu Yang, Yuhang Yao, Adam C Sedgwick, Cuicui Li, Ye Xia, Yan Wang, Lei Kang, Hongmei Su, Bing-Wu Wang, Song Gao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Nickel(II) Phototheranostics: A Case Study in Photoactivated HJournal of the American Chemical Society · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Oxazolochlorins 21. Most Efficient Access toMolecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zi-Shu YangBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 P. R. China zhangjunlong@pku.edu.cn.
Yuhang YaoBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 P. R. China zhangjunlong@pku.edu.cn.
Adam C SedgwickDepartment of Chemistry, The University of Texas at Austin 105 East 24th Street-A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu.ORCID https://orcid.org/0000-0002-3132-2913
Cuicui LiDepartment of Nuclear Medicine, Peking University First Hospital Beijing 100034 P. R. China kanglei@bjmu.edu.cn.
Ye XiaCollege of Chemistry, Beijing Normal University , Beijing 100875 P. R. China.
Yan WangBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 P. R. China zhangjunlong@pku.edu.cn.
Lei KangDepartment of Nuclear Medicine, Peking University First Hospital Beijing 100034 P. R. China kanglei@bjmu.edu.cn.
Hongmei SuCollege of Chemistry, Beijing Normal University , Beijing 100875 P. R. China.ORCID https://orcid.org/0000-0001-7384-6523
Bing-Wu WangBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 P. R. China zhangjunlong@pku.edu.cn.
Song GaoBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 P. R. China zhangjunlong@pku.edu.cn.ORCID https://orcid.org/0000-0002-0039-6346
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin 105 East 24th Street-A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu.ORCID https://orcid.org/0000-0002-9576-1325
Jun-Long ZhangBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University Beijing 100871 P. R. China zhangjunlong@pku.edu.cn.ORCID https://orcid.org/0000-0002-5731-7354

Funding

Biomedical Applications of Expanded Porphyrins: Development of Gold-Texaphyrin ConjugatesR01CA068682 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI Esther Y. Maier, Emily L Que · 1995 to 2026
$7.4M
NCI NIH HHS R01 CA068682
6 · The paper itself

Abstract

We report here porphodilactol derivatives and their corresponding metal complexes. These systems show promise as "all-in-one" phototheranostics and are predicated on a design strategy that involves controlling the relationship between intersystem crossing (ISC) and photothermal conversion efficiency following photoexcitation. The requisite balance was achieved by tuning the aromaticity of these porphyrinoid derivatives and forming complexes with one of two lanthanide cations, namely Gd

Identifiers

PMID34123091
PMCPMC8163340

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.