Evidence map›Paper›PMID 34123087›Full record

ArticleChemical science2020

Tuning molecular aggregation to achieve highly bright AIE dots for NIR-II fluorescence imaging and NIR-I photoacoustic imaging.

Yanzi Xu, Chunbin Li, Ruohan Xu, Ning Zhang, Zhi Wang, Xunan Jing, Zhiwei Yang, Dongfeng Dang, Pengfei Zhang, Lingjie Meng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Advanced Imaging Strategies Based on Intelligent Micro/Nanomotors.Cyborg and bionic systems (Washington, D.C.) · 2025
    Review
  4. Review
  5. Article
  6. Brightness of fluorescent organic nanomaterials.Chemical Society reviews · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Recent advances in aggregation-induced emission luminogens in photoacoustic imaging.European journal of nuclear medicine and molecular imaging · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Dithieno[3,2-RSC advances · 2021
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanzi XuSchool of Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, Xi'an Jiao Tong University Xi'an 710049 P. R. China dongfengdang@xjtu.edu.cn menglingjie@xjtu.edu.cn.
Chunbin LiGuangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Shenzhen 518055 P. R. China pf.zhang@siat.ac.cn.
Ruohan XuSchool of Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, Xi'an Jiao Tong University Xi'an 710049 P. R. China dongfengdang@xjtu.edu.cn menglingjie@xjtu.edu.cn.
Ning ZhangSchool of Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, Xi'an Jiao Tong University Xi'an 710049 P. R. China dongfengdang@xjtu.edu.cn menglingjie@xjtu.edu.cn.
Zhi WangSchool of Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, Xi'an Jiao Tong University Xi'an 710049 P. R. China dongfengdang@xjtu.edu.cn menglingjie@xjtu.edu.cn.
Xunan JingSchool of Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, Xi'an Jiao Tong University Xi'an 710049 P. R. China dongfengdang@xjtu.edu.cn menglingjie@xjtu.edu.cn.
Zhiwei YangSchool of Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, Xi'an Jiao Tong University Xi'an 710049 P. R. China dongfengdang@xjtu.edu.cn menglingjie@xjtu.edu.cn.
Dongfeng DangSchool of Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, Xi'an Jiao Tong University Xi'an 710049 P. R. China dongfengdang@xjtu.edu.cn menglingjie@xjtu.edu.cn.
Pengfei ZhangGuangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Shenzhen 518055 P. R. China pf.zhang@siat.ac.cn.ORCID https://orcid.org/0000-0003-0390-3806
Lingjie MengSchool of Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, Xi'an Jiao Tong University Xi'an 710049 P. R. China dongfengdang@xjtu.edu.cn menglingjie@xjtu.edu.cn.ORCID https://orcid.org/0000-0003-0428-9780

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, bright aggregation-induced emission luminogens (AIEgens) with high photoluminescence quantum yields (PLQYs) in the NIR-II region are still limited, and thus an efficient strategy to enhance NIR-II fluorescence performance through tuning molecular aggregation is proposed here. The synthesized donor-acceptor tailored AIEgen (DTPA-TBZ) not only exhibits an excellent absorptivity in the NIR-I region, but also good fluorescence signals in the NIR-II region with an emission extending to 1200 nm. Benefiting from such improved intramolecular restriction and aggregation, a significant absolute PLQY value of 8.98% was obtained in solid DTPA-TBZ. Encouragingly, the resulting AIE dots also exhibit a high relative PLQY of up to 11.1% with IR 26 as the reference (PLQY = 0.5%). Finally, the AIE dots were applied in high performance NIR-II fluorescence imaging and NIR-I photoacoustic (PA) imaging: visualization of abdominal vessels, hind limb vasculature, and cerebral vessels with high signal to background ratios was performed

Identifiers

PMID34123087
PMCPMC8163436

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.