ArticleChemical science2019
Single molecule observation of hard-soft-acid-base (HSAB) interaction in engineered
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
18 citing papers in PubMed, 75 citations in OpenAlex.
- The accessory role of the outer membrane porin protein MspD inMicrobiology (Reading, England) · 2026Article
- Bioinformatic and computational biophysics tools for nanopore engineering: a review from standard approaches to machine learning advancements.Journal of nanobiotechnology · 2026Review
- Hydrated metal charge density as a universal descriptor explaining mechanistic variations in periodate activation toward pollutant degradation.Nature communications · 2026Article
- The Potential of Nanopore Technologies in Peptide and Protein Sensing for Biomarker Detection.Biosensors · 2025Review
- Synthesis of the NiO-Faujasite Nanocatalyst for Dry Reforming of Methane: The Effect of the Aniline Additive.ACS omega · 2025Article
- Nanopore Environmental Analysis.JACS Au · 2025Review
- Optical Monitoring of Labile Zinc inside Metastatic Cells with Plasmonic Chemonanosensors.ACS omega · 2024Article
- Probe-assisted detection of FeBiosensors & bioelectronics · 2024Article
- Nanopore analysis of cis-diols in fruits.Nature communications · 2024Article
- Biochar and organic fertilizer drive the bacterial community to improve the productivity and quality ofFrontiers in microbiology · 2023Article
- Portable nanopore-sequencing technology: Trends in development and applications.Frontiers in microbiology · 2023Review
- Nanocellulose-Based Adsorbents for Heavy Metal Ion.Polymers · 2022Review
- Preparation ofBiophysics reports · 2021Article
- Review
- Non-Hydroxamate Zinc-Binding Groups as Warheads for Histone Deacetylases.Molecules (Basel, Switzerland) · 2021Review
- Recent advances in biological nanopores for nanopore sequencing, sensing and comparison of functional variations in MspA mutants.RSC advances · 2021Review
- Rapid and multiplex preparation of engineeredChemical science · 2021Article
- Real-time sensing of neurotransmitters by functionalized nanopores embedded in a single live cell.Molecular biomedicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the formation of coordination interactions between metal ions and amino acids in natural metalloproteins, the bound metal ion is critical either for the stabilization of the protein structure or as an enzyme co-factor. Though extremely small in size, metal ions, when bound to the restricted environment of an engineered biological nanopore, result in detectable perturbations during single channel recordings. All reported work of this kind was performed with engineered α-hemolysin nanopores and the observed events appear to be extremely small in amplitude (∼1-3 pA). We speculate that the cylindrical pore restriction of α-hemolysin may not be optimal for probing extremely small analytes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.