Evidence map›Paper›PMID 34122976›Full record

ArticleChemical science2020

N

Nnamdi Akporji, Ruchita R Thakore, Margery Cortes-Clerget, Joel Andersen, Evan Landstrom, Donald H Aue, Fabrice Gallou, Bruce H Lipshutz

Abstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Pd-Catalyzed Heteroannulation UsingJournal of the American Chemical Society · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nnamdi AkporjiDepartment of Chemistry & Biochemistry, University of California Santa Barbara Santa Barbara CA 93106 USA lipshutz@chem.ucsb.edu.ORCID https://orcid.org/0000-0002-0232-8099
Ruchita R ThakoreDepartment of Chemistry & Biochemistry, University of California Santa Barbara Santa Barbara CA 93106 USA lipshutz@chem.ucsb.edu.
Margery Cortes-ClergetNovartis Pharma AG Basel Switzerland.ORCID https://orcid.org/0000-0002-8358-1925
Joel AndersenDepartment of Chemistry, University of Cincinnati, Cincinnati OH 45221 USA.
Evan LandstromDepartment of Chemistry & Biochemistry, University of California Santa Barbara Santa Barbara CA 93106 USA lipshutz@chem.ucsb.edu.ORCID https://orcid.org/0000-0002-5789-6106
Donald H AueDepartment of Chemistry & Biochemistry, University of California Santa Barbara Santa Barbara CA 93106 USA lipshutz@chem.ucsb.edu.ORCID https://orcid.org/0000-0002-2036-523X
Fabrice GallouNovartis Pharma AG Basel Switzerland.ORCID https://orcid.org/0000-0001-8996-6079
Bruce H LipshutzDepartment of Chemistry & Biochemistry, University of California Santa Barbara Santa Barbara CA 93106 USA lipshutz@chem.ucsb.edu.ORCID https://orcid.org/0000-0001-9116-7049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new biaryl phosphine-containing ligand from an active palladium catalyst for ppm level Suzuki-Miyaura couplings, enabled by an aqueous micellar reaction medium. A wide array of functionalized substrates including aryl/heteroaryl bromides are amenable, as are, notably, chlorides. The catalytic system is both general and highly effective at low palladium loadings (1000-2500 ppm or 0.10-0.25 mol%). Density functional theory calculations suggest that greater steric congestion in N

Identifiers

PMID34122976
PMCPMC8159421

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.