ArticleChemical science2020
Metal-free carbon monoxide-releasing micelles undergo tandem photochemical reactions for cutaneous wound healing.
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Thermal CO Release Reactivity of a π-Extended Flavonol Anion.Organic letters · 2024Article
- Iron Porphyrin-mediated Production of Carbon Monoxide from Phenylpyruvic Acid: From Potential Therapeutic and Diagnostic Use to Physiological Implications.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2024Article
- Multiple Applications of a Novel Fluorescence Probe with Large Stokes Shift and Sensitivity for Rapid HJournal of fluorescence · 2024Article
- Recent advances in carbon monoxide-releasing nanomaterials.Bioactive materials · 2024Review
- Engineering Photothermal Catalytic COAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Visible Tracking of Small Molecules of Gases with Fluorescent Donors.Chemical & biomedical imaging · 2024Review
- Fluorescent small molecule donors.Chemical Society reviews · 2024Review
- The potential of nanomedicines for delivery of gaseous signaling molecules.Nanomedicine (London, England) · 2024Article
- An ischemic area-targeting, peroxynitrite-responsive, biomimetic carbon monoxide nanogenerator for preventing myocardial ischemia-reperfusion injury.Bioactive materials · 2023Article
- Intelligent polymeric hydrogen sulfide delivery systems for therapeutic applications.Bioactive materials · 2023Review
- Therapeutic gas-releasing nanomedicines with controlled release: Advances and perspectives.Exploration (Beijing, China) · 2022Review
- Photo-Responsive Micelles with Controllable and Co-Release of Carbon Monoxide, Formaldehyde and Doxorubicin.Polymers · 2022Article
- Activated charcoal dispersion of carbon monoxide prodrugs for oral delivery of CO in a pill.International journal of pharmaceutics · 2022Article
- Flavonol-Based Carbon Monoxide Delivery Molecule with Endoplasmic Reticulum, Mitochondria, And Lysosome Localization.ACS medicinal chemistry letters · 2022Article
- Signaling pathways in cutaneous wound healing.Frontiers in physiology · 2022Review
- Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.Chemical reviews · 2020Article
- Development of Triggerable, Trackable, and Targetable Carbon Monoxide Releasing Molecules.Accounts of chemical research · 2020Article
- Engineering Metal-Organic Frameworks (MOFs) for Controlled Delivery of Physiological Gaseous Transmitters.Nanomaterials (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon monoxide (CO) has shown broad biomedical applications. The site-specific delivery and controlled release of CO is of crucial importance to achieve maximum therapeutic benefits. The development of carbon monoxide (CO)-releasing polymers (CORPs) can increase the stability, optimize pharmacokinetic behavior, and reduce the side effects of small molecule precursors. However, almost all established CORPs were synthesized through a post functional approach, although the direct polymerization strategy is more powerful in controlling the chain compositions and architectures. Herein, a direct polymerization strategy is proposed toward metal-free CO-releasing polymers (CORPs) based on photoresponsive 3-hydroxyflavone (3-HF) derivatives. Such CO-releasing amphiphiles self-assemble into micelles, having excellent water-dispersity. Intriguingly, photo-triggered tandem photochemical reactions confer successive fluorescence transitions from blue-to-red-to-colorless, enabling self-reporting CO release
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.