Evidence map›Paper›PMID 34122886›Full record

ReviewChemical science2020

Recent developments in nickel-catalyzed intermolecular dicarbofunctionalization of alkenes.

Joseph Derosa, Omar Apolinar, Taeho Kang, Van T Tran, Keary M Engle

Abstract readReview
In one paragraph

Review in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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  5. Article
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  7. Article
  8. Nickel-Catalyzed Twofold Conjunctive Coupling via Philicity-Alternating Radical Relay.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. ACS central science · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Reverse Regioselective Dicarbofunctionalization via Anti-Michael-Type Addition.Angewandte Chemie (International ed. in English) · 2025
    Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph DerosaDepartment of Chemistry, The Scripps Research Institute 10550 North Torrey Pines Road, La Jolla California 92037 USA keary@scripps.edu.
Omar ApolinarDepartment of Chemistry, The Scripps Research Institute 10550 North Torrey Pines Road, La Jolla California 92037 USA keary@scripps.edu.
Taeho KangDepartment of Chemistry, The Scripps Research Institute 10550 North Torrey Pines Road, La Jolla California 92037 USA keary@scripps.edu.
Van T TranDepartment of Chemistry, The Scripps Research Institute 10550 North Torrey Pines Road, La Jolla California 92037 USA keary@scripps.edu.
Keary M EngleDepartment of Chemistry, The Scripps Research Institute 10550 North Torrey Pines Road, La Jolla California 92037 USA keary@scripps.edu.ORCID https://orcid.org/0000-0003-2767-6556

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nickel-catalyzed three-component alkene difunctionalization has rapidly emerged as a powerful tool for forging two C-C bonds in a single reaction. Building upon the powerful modes of bond construction in traditional two-component cross-coupling, various research groups have demonstrated the versatility of nickel in enabling catalytic 1,2-dicarbofunctionalization using a wide range of carbon-based electrophiles and nucleophiles and in a fully intermolecular fashion. Though this area has emerged only recently, the last few years have witnessed a proliferation of publications on this topic, underscoring the potential of this strategy to develop into a general platform that offers high regio- and stereoselectivity. This minireview highlights the recent progress in the area of intermolecular 1,2-dicarbofunctionalization of alkenes

Identifiers

PMID34122886
PMCPMC8152638

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.