ArticleChemical science2020
Base-triggered self-amplifying degradable polyurethanes with the ability to translate local stimulation to continuous long-range degradation.
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 34 citations in OpenAlex.
- Self-Immolative Gels: Programmable Degradation Using Self-Immolative Linkers and Polymers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- UV-Triggered Cascading Degradation of Silicone Elastomer via Self-Fluoride Amplification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Biomimetic Non-ergodic Aging by Dynamic-to-covalent Transitions in Physical Hydrogels.ACS applied materials & interfaces · 2024Article
- Thiol-triggered deconstruction of bifunctional silyl ether terpolymersChemical science · 2023Article
- Hydrolytically Stable and Thermo-Mechanically Tunable Poly(Urethane) Thermoset Networks that Selectively Degrade and Generate Reusable Molecules.ACS applied materials & interfaces · 2022Article
- Chain-Growth Sulfur(VI) Fluoride Exchange Polycondensation: Molecular Weight Control and Synthesis of Degradable Polysulfates.ACS central science · 2021Article
- Synthesis of degradable and chemically recyclable polymers using 4,4-disubstituted five-membered cyclic ketene hemiacetal ester (CKHE) monomers.Chemical science · 2021Article
- Chemically fueled materials with a self-immolative mechanism: transient materials with a fast on/off response.Chemical science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
A new type of base-triggered self-amplifying degradable polyurethane is reported that degrades under mild conditions, with the release of increasing amounts of amine product leading to self-amplified degradation. The polymer incorporates a base-sensitive Fmoc-derivative into every repeating unit to enable highly sensitive amine amplified degradation. A sigmoidal degradation curve for the linear polymer was observed consistent with a self-amplifying degradation mechanism. An analogous cross-linked polyurethane gel was prepared and also found to undergo amplified breakdown. In this case, a trace amount of localized base initiates the degradation, which in turn propagates through the material in an amplified manner. The results demonstrate the potential utility of these new generation polyurethanes in enhanced disposability and as stimuli responsive materials.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.