ArticleChemical science2020
Self-division of giant vesicles driven by an internal enzymatic reaction.
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 98 citations in OpenAlex.
- Devising a divisome for synthetic cells.Nature reviews. Chemistry · 2026Review
- Article
- Reconstituting alternative life using the test-bed of cell-free systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Flippase-Mediated Hybrid Vesicle Division.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Protocell Dynamics: Modelling Growth and Division of Lipid Vesicles Driven by an Autocatalytic Reaction.Life (Basel, Switzerland) · 2025Article
- Self-growing protocell models in aqueous two-phase system induced by internal DNA replication reaction.Nature communications · 2025Article
- Spatiotemporal patterns in active four-state Potts models.Scientific reports · 2025Article
- Adaptive metal ion transport and metalloregulation-driven differentiation in pluripotent synthetic cells.Nature chemistry · 2025Article
- Peptide-Induced Division of Polymersomes for Biomimetic Compartmentalization.Angewandte Chemie (International ed. in English) · 2024Article
- Internal State of Vesicles Affects Higher Order State of Vesicle Assembly and Interaction.ACS omega · 2024Article
- Spatiotemporal Communication in Artificial Cell Consortia for Dynamic Control of DNA Nanostructures.ACS central science · 2024Article
- Investigation of artificial cells containing the Par system for bacterial plasmid segregation and inheritance mimicry.Nature communications · 2024Article
- Shocker─A Molecular Dynamics Protocol and Tool for Accelerating and Analyzing the Effects of Osmotic Shocks.Journal of chemical theory and computation · 2024Article
- Engineering Tissue-Scale Properties with Synthetic Cells: Forging One from Many.ACS synthetic biology · 2023Review
- Survival strategies of artificial active agents.Scientific reports · 2023Article
- Synthesising a minimal cell with artificial metabolic pathways.Communications chemistry · 2023Article
- Light-Switchable Membrane Permeability in Giant Unilamellar Vesicles.Pharmaceutics · 2022Article
- Evolution of Proliferative Model Protocells Highly Responsive to the Environment.Life (Basel, Switzerland) · 2022Review
- Growth, replication and division enable evolution of coacervate protocells.Chemical communications (Cambridge, England) · 2022Review
- Shape Deformation, Budding and Division of Giant Vesicles and Artificial Cells: A Review.Life (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Self-division is one of the most common phenomena in living systems and one of the most important properties of life driven by internal mechanisms of cells. Design and engineering of synthetic cells from abiotic components can recreate a life-like function thus contributing to the understanding of the origin of life. Existing methods to induce the self-division of vesicles require external and non-autonomous triggers (temperature change and the addition of membrane precursors). Here we show that pH-responsive giant unilamellar vesicles on the micrometer scale can undergo self-division triggered by an internal autonomous chemical stimulus driven by an enzymatic (urea-urease) reaction coupled to a cross-membrane transport of the substrate, urea. The bilayer of the artificial cells is composed of a mixture of phospholipids (POPC, 1-palmitoyl-2-oleoyl-
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.