Evidence map›Paper›PMID 34122808›Full record

ArticleChemical science2020

3-Bromotetrazine: labelling of macromolecules

Simon D Schnell, Lukas V Hoff, Advaita Panchagnula, Maximilian H H Wurzenberger, Thomas M Klapötke, Simon Sieber, Anthony Linden, Karl Gademann

Abstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. RSC chemical biology · 2023
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Simon D SchnellUniversity of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland Karl.Gademann@uzh.ch.ORCID https://orcid.org/0000-0002-0734-9462
Lukas V HoffUniversity of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland Karl.Gademann@uzh.ch.ORCID https://orcid.org/0000-0002-6135-7594
Advaita PanchagnulaUniversity of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland Karl.Gademann@uzh.ch.ORCID https://orcid.org/0000-0002-4496-4480
Maximilian H H WurzenbergerLudwig-Maximilians-Universität Butenandtstrasse 5-13 81377 Munich Germany.ORCID https://orcid.org/0000-0002-5494-9903
Thomas M KlapötkeLudwig-Maximilians-Universität Butenandtstrasse 5-13 81377 Munich Germany.ORCID https://orcid.org/0000-0003-3276-1157
Simon SieberUniversity of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland Karl.Gademann@uzh.ch.ORCID https://orcid.org/0000-0003-1763-2525
Anthony LindenUniversity of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland Karl.Gademann@uzh.ch.ORCID https://orcid.org/0000-0002-9343-9180
Karl GademannUniversity of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland Karl.Gademann@uzh.ch.ORCID https://orcid.org/0000-0003-3053-0689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the synthesis and first characterisation of the novel chemical probe 3-bromotetrazine and establish its reactivity towards nucleophiles. This led to the synthesis of several novel classes of 3-monosubstituted

Identifiers

PMID34122808
PMCPMC8157750

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.