ArticleChemical science2020
Electrostatically-directed Pd-catalysis in combination with C-H activation: site-selective coupling of remote chlorides with fluoroarenes and fluoroheteroarenes.
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 40 citations in OpenAlex.
- An Enantioselective Alkene Aminoarylation to Form Chiral Indolines via Electrostatically-Directed Palladium Catalysis.Angewandte Chemie (International ed. in English) · 2026Article
- Optimization of a Resolution Process Allowing Access to Both Enantiomers of the Versatile Chiral Phosphine Ligand sSPhos on Scale.Organic process research & development · 2026Article
- Asymmetric Desymmetrizing Sulfonylation of Diarylmethanes via Peptidyl-Cu(I)-Catalysis with Remote Stereocontrol.Journal of the American Chemical Society · 2026Article
- Enantioselective Formal Synthesis of (-)-Aflatoxin BOrganic letters · 2025Article
- Design Approaches That Utilize Ionic Interactions to Control Selectivity in Transition Metal Catalysis.Chemical reviews · 2025Review
- Intermolecular Asymmetric Arylative Dearomatization of 1-Naphthols.Journal of the American Chemical Society · 2024Article
- Application of sSPhos as a Chiral Ligand for Palladium-Catalyzed Asymmetric Allylic Alkylation.Organic letters · 2024Article
- Kinetically controlled synthesis of rotaxane geometric isomers.Chemical science · 2024Article
- sSPhos: A General Ligand for Enantioselective Arylative Phenol Dearomatization via Electrostatically-Directed Palladium Catalysis.Journal of the American Chemical Society · 2023Article
- Amino Acid-Derived Ionic Chiral Catalysts Enable Desymmetrizing Cross-Coupling to Remote Acyclic Quaternary Stereocenters.Journal of the American Chemical Society · 2023Article
- An Enantioselective Suzuki-Miyaura Coupling To Form Axially Chiral Biphenols.Journal of the American Chemical Society · 2022Article
- Site-Selective Cross-Coupling of Polyhalogenated Arenes and Heteroarenes with Identical Halogen Groups.Chemical reviews · 2022Review
- Empirical Guidelines for the Development of Remote Directing Templates through Quantitative and Experimental Analyses.Journal of the American Chemical Society · 2022Article
- Distal Ionic Substrate-Catalyst Interactions Enable Long-Range Stereocontrol: Access to Remote Quaternary Stereocenters through a Desymmetrizing Suzuki-Miyaura Reaction.Journal of the American Chemical Society · 2022Article
- Amphiphilic Biaryl Monophosphine Ligands by Regioselective Sulfonation.Organic letters · 2021Article
- Quantifying Through-Space Substituent Effects.Angewandte Chemie (International ed. in English) · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systems incorporating catalyst-substrate non-covalent interactions are emerging as a versatile approach to address site-selectivity challenges in remote functionalization reactions. Given the achievements that have been made in this regard using metals such as iridium, manganese and rhodium, it is surprising that non-covalent catalyst direction has not been utilized in reactions incorporating palladium-catalyzed C-H activation steps, despite palladium being arguably the most versatile metal for C-H activation. Herein, we demonstrate that electrostatically directed, site-selective C-Cl oxidative addition is compatible with a subsequent C-H activation step, proceeding
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.