Evidence map›Paper›PMID 34122804›Full record

ArticleChemical science2020

Visualizing intracellular particles and precise control of drug release using an emissive hydrazone photochrome.

Xing Guo, Baihao Shao, Shaobing Zhou, Ivan Aprahamian, Zi Chen

Abstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Dynamic Control of Nucleic Acids Self-Assembly and Expression Using Photoswitches.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Article
  3. Journal of the American Chemical Society · 2026
    Article
  4. Article
  5. Molecular Steganography Using Multistate Photoswitchable Hydrazones.Journal of the American Chemical Society · 2025
    Article
  6. Article
  7. Article
  8. Recent Progress in Photoresponsive Biomaterials.Molecules (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Molecular photoswitches in aqueous environments.Chemical Society reviews · 2021
    Review
  11. Trace mild acid-catalysedChemical science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xing GuoKey Laboratory of Advanced Technologies of Materials Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University Chengdu 610031 China shaobingzhou@swjtu.edu.cn.
Baihao ShaoDepartment of Chemistry, Dartmouth College Hanover New Hampshire 03755 USA ivan.aprahamian@dartmouth.edu.
Shaobing ZhouKey Laboratory of Advanced Technologies of Materials Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University Chengdu 610031 China shaobingzhou@swjtu.edu.cn.
Ivan AprahamianDepartment of Chemistry, Dartmouth College Hanover New Hampshire 03755 USA ivan.aprahamian@dartmouth.edu.ORCID https://orcid.org/0000-0003-2399-8208
Zi ChenThayer School of Engineering, Dartmouth College Hanover New Hampshire 03755 USA zi.chen@dartmouth.edu.ORCID https://orcid.org/0000-0001-5927-0249

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spatiotemporal control over the structure of nanoparticles while monitoring their localization in tumor cells can improve the precision of controlled drug release, thus enhancing the efficiency of drug delivery. Here, we report on a photochromic nanoparticle system (

Identifiers

PMID34122804
PMCPMC8157519

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.