ArticleInternational journal of exercise science2021
The 6-week Effects of HIIT on Biomarkers of Tissue and Oxidative Damage in Wistar Rats Previously Supplemented with Pyridoxine.
Article in International journal of exercise science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A Review of Mechanisms Underlying Modulation of Cardiorespiratory Endurance and Psychological Stress in College Students by High-Intensity Interval Training (HIIT) Combined with B-Vitamin Supplementation.Healthcare (Basel, Switzerland) · 2025Review
- Strength Training Protects High-Fat-Fed Ovariectomized Mice against Insulin Resistance and Hepatic Steatosis.International journal of molecular sciences · 2024Article
- 12 Weeks of Physical Exercise Attenuates Oxidative Stress, Improves Functional Tests Performance, and Reduces Fall Risk in Elderly Women Independently on Serum 25(OH)D Concentration.Frontiers in physiology · 2022Article
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Authors and funding
8 authors.
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Abstract
We aimed to analyze the effects of long high-intensity interval training (HIIT) associated with pyridoxin supplementation on tissue and oxidative injury markers in animals. Male Wistar rats were divided into three groups (n = 8): sedentary (GS), HIIT (GH), and HIIT + pyridoxine (GHP). The HIIT comprised 18 sessions of 7 repetitions of 2min × 2min rest, 3 times per week. Pyridoxine was administered to the GHP group 1h before the exercise. The Thiobarbituric acid reactive substances (TBARS) and sulfhydryl group (SH) were analyzed as markers of oxidative stress and CK, LDH, ALT and AST as tissue lesions. There was an increase in the correlation between CK and LDH of 172.86% and 268.83% in the GH group compared with the GS group, respectively. There was a reduction in CK (34.37%) and LDH (34.74%) compared with the GH group, which had an increase of 229.03% in ALT. Pyridoxine supplementation reduced ALT by 80.62% in the GHP group compared with no-supplementation GH group. In addition, there was a reduction in plasma MDA (52.92%), liver (20.30%) and cardiac (22.06%) tissues in GHP compared to GH. It was possible to conclude that administration of pyridoxine attenuated oxidative stress, and tissue injuries induced by HIIT.
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