Evidence map›Paper›PMID 34122672›Full record

ReviewBiocatalysis and agricultural biotechnology2021

Evidence-based traditional Siddha formulations for prophylaxis and management of respiratory symptoms in COVID-19 pandemic-a review.

P Prakash, R Meena, L Stanley Abraham, Swetha Sunkar, K Govindaraju, Durgasruthi Pully, Antony V Samrot

Open access · greenAbstract readReview
In one paragraph

Review in Biocatalysis and agricultural biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

P PrakashDepartment of Biotechnology, School of Bio and Chemical of Engineering, Sathyabama Institute of Science and Technology, Chennai, 600 119, Tamilnadu, India.
R MeenaSiddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Arumbakkam, Chennai, 600106, India.
L Stanley AbrahamCentre for Ocean Research, Sathyabama Institute of Science and Technology, Chennai, 600 119, Tamilnadu, India.
Swetha SunkarCenter for Molecular Data Science and Systems Biology, Department of Bioinformatics, Sathyabama Institute of Science and Technology, Chennai, 600 119, Tamilnadu, India.
K GovindarajuCentre for Ocean Research, Sathyabama Institute of Science and Technology, Chennai, 600 119, Tamilnadu, India.
Durgasruthi PullyFaculty of Science, KU Leuven, Leuven-3000, Belgium.
Antony V SamrotSchool of Bioscience, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Jalan SP2, Bandar Saujana Putra, 42610, Jenjarom, Selangor, Malaysia.
Sathyabama Institute of Science and Technology · INGovernment of India · INKU Leuven · BEMahsa University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent outbreak of COVID-19 is attributed to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This viral disease is rapidly spreading across the globe, including India. The mainstay in managing the disease is supportive care, nutrition, and preventing further progression in the absence of proven antiviral drugs. Currently two vaccines Covishield and Covaxin are administered in India. Long-term plans of developing most reliable mRNA-based vaccines are also underway for the future method of prophylaxis. The Siddha system of medicine's holistic approach emphasizes lifestyle modification, prophylactic interventions, and dietary management to boost the host immunity and treatment with herbal medicines and higher-order medicines as the case may be. In this review, a brief outline of the disease COVID-19, Coronavirus, evidence-based traditional Siddha interventions for respiratory ailments and immune boosters highlighting the relevant published research on individual herbs are dealt, which pave way for further research on drug repurposing for COVID-19. Historical evidence on the prevention and treatment of infections especially antivirals in Siddha classics is studied.

Indexed as

Antiviral propertyCOVID - 19Immunomodulatory drugsPandemicSARS-CoV-2Siddha

Identifiers

PMID34122672
PMCPMC8180453
OpenAlexW3170129628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.