Evidence map›Paper›PMID 34122669›Full record

ArticleDisease markers2021

Prognostic Value of the Red Cell Distribution Width in Patients with Sepsis-Induced Acute Respiratory Distress Syndrome: A Retrospective Cohort Study.

Huabin Wang, Junbin Huang, Wenhua Liao, Jiannan Xu, Zhongyuan He, Yong Liu, Zhijie He, Chun Chen

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Huabin WangDivision of Hematology/Oncology, Department of Pediatrics, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, China.
Junbin HuangDivision of Hematology/Oncology, Department of Pediatrics, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, China.
Wenhua LiaoDepartment of Intensive Care Unit, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou 510000, China.
Jiannan XuCenter of Digestive Disease, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, China.
Zhongyuan HeDepartment of Orthopedics, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, China.
Yong LiuDivision of Hematology/Oncology, Department of Pediatrics, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, China.
Zhijie HeDepartment of Intensive Care Unit, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou 510000, China.ORCID https://orcid.org/0000-0003-4529-8958
Chun ChenDivision of Hematology/Oncology, Department of Pediatrics, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen 518107, China.ORCID https://orcid.org/0000-0002-9800-4012
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe prognostic value of the red cell distribution width (RDW) in patients with sepsis-induced acute respiratory distress syndrome (ARDS) is still elusive. This study is aimed at determining whether RDW is a prognostic indicator of sepsis-induced ARDS.

methodsThis retrospective cohort study included 1161 patients with sepsis-induced ARDS. The datasets were acquired from the Medical Information Mart for Intensive Care III database. The locally weighted scatter-plot smoothing technique, Cox regression, Kaplan-Meier estimator, and subgroup analysis were carried out to evaluate the association between RDW and 90-day mortality.

resultsThe RDW and mortality had a roughly linear increasing relationship. The Cox regression model results were as follows: for level 2 (14.5% < RDW < 16.2%), hazard ratio (HR) = 1.35, 95% confidence interval (CI) = 1.03-1.77, and for level 3 (RDW ≥ 16.2%), HR = 2.07, 95% CI = 1.59-2.69. The following results were obtained when RDW was treated as a continuous variable: HR = 1.11, 95%CI = 1.06-1.15. The

conclusionRDW is a new independent prognostic marker for patients with sepsis-induced ARDS.

Indexed as

Erythrocyte IndicesAdolescentAdultAgedAged, 80 and overDatabases, FactualFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRespiratory Distress SyndromeRetrospective StudiesSepsisSurvival Analysis

Identifiers

PMID34122669
PMCPMC8189810
OpenAlexW3168804830

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.