Evidence map›Paper›PMID 34122612›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Chemical Composition and Antimicrobial Activity of Two Sri Lankan Lichens,

Polwatta Samaraweera Arachchige Ishara Shiromi, Ruwani Punyakanthi Hewawasam, Rankoth Gedara Udeni Jayalal, Hasanga Rathnayake, Weerasinghe Mudiyanselage Dilip Gaya Bandara Wijayaratne, Dakshika Wanniarachchi

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Unassuming Lichens: Nature's Hidden Antimicrobial Warriors.International journal of molecular sciences · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Polwatta Samaraweera Arachchige Ishara ShiromiDepartment of Natural Resources, Faculty of Applied Sciences, Sabaragamuwa University of Sri Lanka, Belihuloya, Sri Lanka.
Ruwani Punyakanthi HewawasamDepartment of Biochemistry, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.ORCID https://orcid.org/0000-0001-6349-4755
Rankoth Gedara Udeni JayalalDepartment of Natural Resources, Faculty of Applied Sciences, Sabaragamuwa University of Sri Lanka, Belihuloya, Sri Lanka.ORCID https://orcid.org/0000-0001-8258-2873
Hasanga RathnayakeDepartment of Biochemistry, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.ORCID https://orcid.org/0000-0003-1994-571X
Weerasinghe Mudiyanselage Dilip Gaya Bandara WijayaratneDepartment of Microbiology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.ORCID https://orcid.org/0000-0002-8330-3597
Dakshika WanniarachchiInstrument Center, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.ORCID https://orcid.org/0000-0001-7944-0954
University of Ruhuna · LKSabaragamuwa University of Sri Lanka · LKUniversity of Sri Jayewardenepura · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMedicinal utility of lichens is ascribed to the presence of various secondary metabolites of low molecular weight and they have been used in traditional medicine including Ayurveda in the treatment of wounds and skin disorders. Despite the urgent need to effectively address the antibiotic resistance worldwide, the discovery of new antibacterial drugs has declined in the recent past. This emphasizes the increasing importance of investigating and developing new classes of antibiotics that can withstand antibiotic resistance.

resultsAlectorialic acid, atranorin, atraric acid, orcinol, and O-orsellinaldehyde were among the secondary metabolites identified by the TLC and GC-MS analysis. None of the lichen extracts were active against Gram-negative bacteria but both lichens showed a concentration-dependent activity against methicillin-sensitive

conclusionBoth lichens,

Identifiers

PMID34122612
PMCPMC8189799
OpenAlexW3166949411

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.