ArticleARYA atherosclerosis2020
Rationale, design, and preliminary results of the Iran-premature coronary artery disease study (I-PAD): A multi-center case-control study of different Iranian ethnicities.
Article in ARYA atherosclerosis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 24 citations in OpenAlex.
- Association Between Fruits and Vegetables Consumption and Premature Coronary Artery Disease (PCAD): A Multi-Center Case Control Study.Food science & nutrition · 2026Article
- The Association Between Atherogenic Index of Plasma and Type 2 Diabetes Mellitus in a Multi-Ethnic Population of Premature Coronary Artery Disease Patients: Insights From IPAD Study.Endocrinology, diabetes & metabolism · 2026Article
- Article
- Cardiovascular health metrics among an Iranian population: insights from life's essential 8.BMC cardiovascular disorders · 2026Article
- Isfahan familial hypercholesterolemia cohort (IFHC) study: Methods, insights and early results.ARYA atherosclerosis · 2026Article
- Association Between PURE Diet Score and Mental Disorders in Patients At-Risk of Cardiovascular Disease: Findings From the Iran Premature Coronary Artery Disease (IPAD) Study, a Multicenter Cross-Sectional Study.Health science reports · 2025Article
- The correlation between PURE healthy diet and premature coronary artery disease: Iran premature coronary artery disease (IPAD) study.BMC cardiovascular disorders · 2025Article
- Sugar-sweetened beverage consumption and risk of premature coronary artery disease in a multi-ethnic Iranian case-control study.Nutrition & metabolism · 2025Article
- Healthy eating behaviors may be associated with lower risk of premature coronary artery disease: A multi-center case-control study.Journal of health, population, and nutrition · 2025Article
- The association between the Mediterranean Diet and the Prime Diet Quality Score and polycystic ovary syndrome: a case control study.BMC nutrition · 2025Article
- Mediterranean diet and prime diet quality score are associated with reduced risk of premature coronary artery disease in Iran: a multi-centric case-control study.Scientific reports · 2025Article
- Investigating ethnic differences in risk factors and severity of developing premature coronary artery disease: Predicting the effect of risk factors through decision tree analysis in a multicenter case-control study; Results from Iran Premature Coronary Artery Disease (IPAD study).Journal of cardiovascular and thoracic research · 2025Article
- Cost-effectiveness and budget impact analysis of rivaroxaban with or without aspirin compared to aspirin alone in patients with coronary and peripheral artery diseases in Iran.BMC health services research · 2025Article
- Dairy consumption and premature coronary artery disease onset: Iran premature coronary artery disease (IPAD) study insights.Scientific reports · 2025Article
- Age at menarche and risk of premature coronary artery disease: results from Iran premature coronary disease (IPAD) study.Archives of gynecology and obstetrics · 2025Article
- Adherence to EAT-Lancet reference diet and risk of premature coronary artery diseases: a multi-center case-control study.European journal of nutrition · 2024Article
- Dietary patterns and premature coronary artery disease: result from the Iran premature coronary artery disease (IPAD) study.BMC cardiovascular disorders · 2024Article
- Preliminary Results of Iran Premature Coronary Artery Disease (IPAD study) and Implementation of IPAD Biobank: A Case-Control Study.Archives of Iranian medicine · 2024Article
- The relationship between fermented and nonfermented dairy products consumption and hypertension among premature coronary artery disease patients: Iran premature coronary artery disease study.Food science & nutrition · 2024Article
- Which risk factor best predicts coronary artery disease using artificial neural network method?BMC medical informatics and decision making · 2024Article
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPremature coronary artery disease (CAD) is still prevalent worldwide and may differ in various ethnicities. Due to the presence of different ethnicities in Iran, the Iran-premature coronary artery disease (I-PAD) study aimed to determine the frequency of premature CAD and related risk factors based on each ethnicity.
methodsIn this multi-center case-control study, 4000 patients with premature CAD from ten different ethnicities who lived in different cities of Iran and underwent coronary angiography were enrolled (women aged ≤ 70 and men ≤ 60 years). Patients with CAD defined as obstruction equal or above 75% in at least a single coronary artery or left main ≥ 50% were included in the case group, while patients with normal coronary arteries were included in the control group. Lifestyle behaviors, cardiometabolic risk factors, anthropometric measurements, and other variables were collected. Serum, whole blood, buffy coat, plasma, urine, stool, and saliva samples were stored.
resultsThe number of patients enrolled until April 2020 was 2071. The mean age of patients was 53.51 ± 7.52 and 934 (45.09%) of patients were women. To date, about 39.6% of the patients were normal. Also, about 26.0% were with one-vessel disease (1VD), 15.0% with two-vessel disease (2VD), and 15.2% with three-vessel disease (3VD). More than 30000 patients' biosamples from across the country have been stored.
conclusionKnowing the frequency of premature CAD according to different ethnicities with major differences in their lifestyle behaviors and risk factors can assist health decision-makers. In addition, I-PAD biosamples will be an invaluable source.
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