ReviewJournal of contemporary brachytherapy2021
Efficacy and complications of ruthenium-106 brachytherapy for uveal melanoma: a systematic review and meta-analysis.
Review in Journal of contemporary brachytherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Efficacy and safety of proton radiotherapy in treating choroidal melanoma: a systematic review and meta-analysis.Radiation oncology (London, England) · 2025Pooled it
- Fractionated stereotactic re-irradiation after plaque radiotherapy (brachytherapy) failure in uveal melanoma.Journal of contemporary brachytherapy · 2026Article
- Article
- Article
- A Brief Overview of Uveal Melanoma Treatment Methods with a Focus on the Latest Advances.Journal of clinical medicine · 2025Article
- Gantry-based pencil beam scanning proton therapy for uveal melanoma: IMPT versus proton arc therapy.Radiation oncology (London, England) · 2025Article
- Proton Therapy in Uveal Melanoma.Cancers · 2024Review
- Plaque Radiotherapy for Ocular Melanoma.Cancers · 2024Review
- Comparison of stereotactic radiotherapy and protons for uveal melanoma patients.Physics and imaging in radiation oncology · 2024Article
- Radiation retinopathy following episcleral brachytherapy for intraocular tumors: Current treatment options.Journal of contemporary brachytherapy · 2023Review
- Subconjunctival Ocular Argyrosis following Treatment with Ruthenium 106 Brachytherapy for Choroidal Melanoma.Ocular oncology and pathology · 2023Article
- Deterioration of Visual Acuity after Brachytherapy and Proton Therapy of Uveal Melanoma, and Methods of Counteracting This Complication Based on Recent Publications.Medicina (Kaunas, Lithuania) · 2023Review
- Long-term visual outcomes after ruthenium plaque brachytherapy for posterior choroidal melanoma.Eye (London, England) · 2023Article
- Anatomical and Functional Outcomes after Endoresection and Adjuvant Ruthenium Brachytherapy for Uveal Melanoma: A Single-Center Experience.Life (Basel, Switzerland) · 2023Article
- Ocular Complications of Radiotherapy in Uveal Melanoma.Cancers · 2023Review
- Clinical Outcomes after Surgical Resection Combined with Brachytherapy for Uveal Melanomas.Journal of clinical medicine · 2022Article
- Radiological and clinical findings in uveal melanoma treated by plaque interventional radiotherapy (brachytherapy): Visual atlas and literature review on response assessment.Journal of contemporary brachytherapy · 2022Article
- Radiobiological evaluation of organs at risk for electronic high-dose-rate brachytherapy in uveal melanoma: a radiobiological modeling study.Journal of contemporary brachytherapy · 2021Article
- High-Dose-Rate Yttrium-90 (Ophthalmology scienceArticle
- Yttrium-90 Episcleral Plaque Brachytherapy for Choroidal Melanoma.Journal of vitreoretinal diseasesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to evaluate the efficacy and vision-threatening complications of brachytherapy with ruthenium-106 ( MATERIAL AND
methodsA literature review was performed based on results from searching PubMed, Embase, Web of Science, Scopus, and Cochrane databases, using the following key words: "choroidal melanoma", "uveal melanoma", "brachytherapy", and "ruthenium-106". We included studies performed on more than 30 patients since 1986, reporting on local control rate, complications rate, mean radiation dose, and mean tumor thickness. The cumulative analysis was performed using Metaprop command of Stata v.16, and meta-regression was conducted based on mean tumor thickness and mean radiation dose to tumor's apex.
resultsTwenty-one retrospective studies were selected, involving 3,913 patients treated primarily with
conclusionsAlthough the studies' heterogeneity was high, in a prescription dose ranging from 70 Gy to 250 Gy to the tumor apex,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.