Evidence map›Paper›PMID 34122539›Full record

ArticleGastroenterology research and practice2021

Effect of Direct-Acting Antiviral Therapy on Thrombocytopenic Patients with Hepatitis C Virus-Related Chronic Liver Disease.

Mahmoud Saif-Al-Islam, Usama M Abdelaal, Mustafa Adel Younis, Hisham A Alghany Algahlan, Safaa Khalaf

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mahmoud Saif-Al-IslamTropical Medicine and Gastroenterology Department, Sohag University Hospital, Faculty of Medicine, Sohag, Egypt.
Usama M AbdelaalInternal Medicine Department, Sohag University Hospital, Faculty of Medicine, Sohag, Egypt.ORCID https://orcid.org/0000-0001-9998-668X
Mustafa Adel YounisClinical and Chemical Pathology Department, Sohag University Hospital, Faculty of Medicine, Sohag, Egypt.
Hisham A Alghany AlgahlanDiagnostic Radiology Department, Sohag University Hospital, Faculty of Medicine, Sohag, Egypt.
Safaa KhalafTropical Medicine and Gastroenterology Department, Sohag University Hospital, Faculty of Medicine, Sohag, Egypt.
Sohag University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThrombocytopenia is a common complication in patients with chronic hepatitis C virus (HCV) that increases the risk of bleeding. We aimed to analyze the hematologic effects of the new direct-acting antiviral (DAA) therapy, particularly on the platelet count in chronic HCV-infected patients with thrombocytopenia.

resultsAt the end of treatment (EOT), there was a highly significant increase in platelet count (

conclusionSofosbuvir-based DAA therapy is a highly effective and safe treatment regimen that results in the improvement of platelet count in thrombocytopenic patients, particularly in mild to moderate stages of hepatic fibrosis.

Identifiers

PMID34122539
PMCPMC8169259
OpenAlexW3165191235

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.