Evidence map›Paper›PMID 34122382›Full record

ArticleFrontiers in microbiology2021

CD8

Amber D Jones, Svetlana Khakhina, Tara Jaison, Erin Santos, Stephen Smith, Zachary A Klase

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amber D JonesDepartment of Biological Sciences, University of the Sciences, Philadelphia, PA, United States.
Svetlana KhakhinaDepartment of Biological Sciences, University of the Sciences, Philadelphia, PA, United States.
Tara JaisonDepartment of Biological Sciences, University of the Sciences, Philadelphia, PA, United States.
Erin SantosThe Smith Center for Infectious Diseases and Urban Health, West Orange, NJ, United States.
Stephen SmithThe Smith Center for Infectious Diseases and Urban Health, West Orange, NJ, United States.
Zachary A KlaseDepartment of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, PA, United States.

Funding

Understanding the overlap of chromatin alteration in HIV-1 and drug abuseDP2DA044550 · NIDA · UNIVERSITY OF THE SCIENCES PHILADELPHIA · PI KLASE, ZACHARY ALAN · 2017 to 2017
$2.1M
NIDA NIH HHS DP2 DA044550
6 · The paper itself

Abstract

A unique population of HIV-1 infected individuals can control infection without antiretroviral therapy. These individuals fall into a myriad of categories based on the degree of control (low or undetectable viral load), the durability of control over time and the underlying mechanism (i.e., possession of protective HLA alleles or the absence of critical cell surface receptors). In this study, we examine a cohort of HIV-1 infected individuals with a documented history of sustained low viral loads in the absence of therapy. Through

Indexed as

CD4:CD8 ratioCD8+ T cellHIV-1HIV controllerHLA compatibilityLow Viral Load

Identifiers

PMID34122382
PMCPMC8192701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.