Evidence map›Paper›PMID 34122361›Full record

ArticleFrontiers in microbiology2021

Bacterial Biofilm Growth on 3D-Printed Materials.

Donald C Hall, Phillip Palmer, Hai-Feng Ji, Garth D Ehrlich, Jarosław E Król

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Donald C HallDepartment of Chemistry, Drexel University, Philadelphia, PA, United States.
Phillip PalmerCenter for Advanced Microbial Processing and Center for Surgical Infections and Biofilms, Institute for Molecular Medicine and Infectious Disease, Department of Microbiology and Immunology, Philadelphia, PA, United States.
Hai-Feng JiDepartment of Chemistry, Drexel University, Philadelphia, PA, United States.
Garth D EhrlichCenter for Advanced Microbial Processing and Center for Surgical Infections and Biofilms, Institute for Molecular Medicine and Infectious Disease, Department of Microbiology and Immunology, Philadelphia, PA, United States.
Jarosław E KrólCenter for Advanced Microbial Processing and Center for Surgical Infections and Biofilms, Institute for Molecular Medicine and Infectious Disease, Department of Microbiology and Immunology, Philadelphia, PA, United States.
Institute for Molecular Medicine · USDrexel University · US

Funding

MOLECULAR ANALYSIS OF PATHOGENS IN OTITIS MEDIA BY PCRR01DC002148 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EHRLICH, GARTH D. · 1994 to 2017
$6.5M
NIDCD NIH HHS R01 DC002148
6 · The paper itself

Abstract

Recent advances in 3D printing have led to a rise in the use of 3D printed materials in prosthetics and external medical devices. These devices, while inexpensive, have not been adequately studied for their ability to resist biofouling and biofilm buildup. Bacterial biofilms are a major cause of biofouling in the medical field and, therefore, hospital-acquired, and medical device infections. These surface-attached bacteria are highly recalcitrant to conventional antimicrobial agents and result in chronic infections. During the COVID-19 pandemic, the U.S. Food and Drug Administration and medical officials have considered 3D printed medical devices as alternatives to conventional devices, due to manufacturing shortages. This abundant use of 3D printed devices in the medical fields warrants studies to assess the ability of different microorganisms to attach and colonize to such surfaces. In this study, we describe methods to determine bacterial biofouling and biofilm formation on 3D printed materials. We explored the biofilm-forming ability of multiple opportunistic pathogens commonly found on the human body including

Indexed as

3D printing3D structuresantimicrobial propertiesbacterial infectionsbiofilmPLA polymersurface topology

Identifiers

PMID34122361
PMCPMC8192718
OpenAlexW3168820445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.