ArticleFrontiers in endocrinology2021
Prevalence of Thyroid Nodules in China: A Health Examination Cohort-Based Study.
Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 91 citations in OpenAlex.
- Trial
- Development of a predictive model using key ultrasound characteristics to distinguish follicular thyroid neoplasms from nodular goiter.Pakistan journal of medical sciences · 2026Article
- Occurrence of clinically relevant thyroid nodules in adults.Radiology and oncology · 2026Article
- Current status of public education on endocrine and metabolic diseases carried out by academic journals' WeChat official accounts: a retrospective study.BMC public health · 2026Article
- Designing and Evaluating an Autoverification RCV-Based System for Thyroid Function Profiles.Diagnostics (Basel, Switzerland) · 2026Article
- Development and validation of a predictive nomogram for high-risk thyroid nodules: a retrospective analysis of sedentary time, insomnia, and elevated weight.Frontiers in oncology · 2026Article
- Clinical outcomes and functional preservation of microwave ablation versus surgical resection for benign thyroid nodules: a propensity score-matched retrospective cohort study.Frontiers in endocrinology · 2026Article
- Four-year trends in health findings among hospital staff an ecological time-series study 2022-2025.Frontiers in public health · 2026Article
- Short-term effect of iodine contrast medium on thyroid function: a prospective cohort study.Annals of medicine · 2025Article
- Urinary iodine levels and thyroid disorder prevalence in the adult population of China: a large-scale population-based cross-sectional study.Scientific reports · 2025Article
- Association between depressive symptoms and thyroid nodule incidence in women: a prospective observational study.BMC public health · 2025Observational
- Prevalence of thyroid nodules and canceration risk assessment in TIRADS, and their relationships to obesity and dysglycemia.Frontiers in oncology · 2025Article
- Pituitary-Thyroid Hormones and Related Indices in Euthyroid Type 2 Diabetes: Association With Thyroid Nodules.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Anxiety disorders in patients with thyroid nodules vs. thyroid cancer: a retrospective cohort study.Frontiers in endocrinology · 2025Article
- A predictive nomogram of thyroid nodules based on deep learning ultrasound image analysis.Frontiers in endocrinology · 2025Article
- Mental Health Status of Patients with Thyroid Nodules: A Cross-Sectional Study.Journal of multidisciplinary healthcare · 2025Article
- Nomogram Prediction Model of Thyroid Nodule in Healthcare Professionals: Based on Physical and Psychological Risk Factors.Risk management and healthcare policy · 2025Article
- Epidemiological and Pathogenic Characteristics of Benign and Malignant Thyroid Nodules Undergoing Ultrasonography for Health Checkup Population.International journal of general medicine · 2025Article
- The association between metal element levels and thyroid nodules in oilfield workers: a cross-sectional study.Frontiers in endocrinology · 2025Article
- Relationship between thyroid nodules and iodine nutritional status, thyroglobulin (Tg), and other influencing factors: a 1:1 matched case-control study.Frontiers in endocrinology · 2025Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Thyroid nodules are a common clinical problem and some are potentially cancerous; however, little is known about the prevalence of thyroid nodules in China. The objective of this study was to investigate the prevalence of thyroid nodules in a healthy Chinese population. Methods: We reviewed electronic medical records of 13,178,313 participants from 30 provinces and regions who received health examinations and underwent thyroid ultrasound at Meinian Onehealth Healthcare in 2017. Among them, 6,192,357 were excluded based on predefined criteria. All thyroid nodules were diagnosed by ultrasonography, and standardized protocols were adopted for data collection, quality control, and data management. Results: A total of 6,985,956 participants (mean age: 42.1 ± 13.1 years) were included in this study. The overall prevalence of thyroid nodules was 36.9% (95% CI, 35.7%-38.1%; age- and sex-standardized prevalence 38.0% [95% CI, 37.0%-39.1%]). The prevalence of thyroid nodules in females (44.7% [95% CI, 43.4%-45.9%], age-standardized prevalence: 45.2% [95% CI, 44.1%-46.4%]) was significantly higher than that in males (29.9% [95% CI, 28.8%-31.0%], age-standardized prevalence 31.2% [95% CI, 30.1%-32.2%]; Conclusion: This study provides the first nationwide analysis of the prevalence of thyroid nodules in China. Our results showed that the prevalence of thyroid nodules was high in health screening Chinese people with regional-specific patterns.
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