Evidence map›Paper›PMID 34122069›Full record

ArticleFrontiers in pharmacology2021

Discovery of Potent EGFR Inhibitors With

Meng Li, Na Xue, Xingang Liu, Qiaoyun Wang, Hongyi Yan, Yifan Liu, Lei Wang, Xiaowei Shi, Deying Cao, Kai Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Nanoselenium attenuates renal ischemia-reperfusion injury in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Meng LiDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Na XueDepartment of Pharmaceutical Engineering, Hebei Chemical and Pharmaceutical College, Shijiazhuang, China.
Xingang LiuDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Qiaoyun WangDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Hongyi YanDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Yifan LiuDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Lei WangDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Xiaowei ShiDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Deying CaoDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Kai ZhangDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Yang ZhangDepartment of Medicinal Chemistry, Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CNHebei Chemical and Pharmaceutical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the classical pharmacophore fusion strategy, a series of

Indexed as

anti-proliferative bioactivitiesEGFRenzyme activity inhibition assaymolecular dockingmolecular dynamic simulation

Identifiers

PMID34122069
PMCPMC8187944
OpenAlexW3164659790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.