Evidence map›Paper›PMID 34122044›Full record

ArticleFrontiers in aging neuroscience2021

Positive Effect of Cognitive Reserve on Episodic Memory, Executive and Attentional Functions Taking Into Account Amyloid-Beta, Tau, and Apolipoprotein E Status.

Justinas Narbutas, Daphne Chylinski, Maxime Van Egroo, Mohamed Ali Bahri, Ekaterina Koshmanova, Gabriel Besson, Vincenzo Muto, Christina Schmidt, André Luxen, Evelyne Balteau and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Justinas NarbutasGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Daphne ChylinskiGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Maxime Van EgrooGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Mohamed Ali BahriGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Ekaterina KoshmanovaGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Gabriel BessonGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Vincenzo MutoGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Christina SchmidtGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
André LuxenGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Evelyne BalteauGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Christophe PhillipsGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Pierre MaquetGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Eric SalmonGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Gilles VandewalleGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Christine BastinGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
Fabienne ColletteGIGA Institute, Cyclotron Research Centre In Vivo Imaging, University of Liège, Liège, Belgium.
University of Liège · BECentre Hospitalier Universitaire de Liège · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies exploring the simultaneous influence of several physiological and environmental factors on domain-specific cognition in late middle-age remain scarce. Therefore, our objective was to determine the respective contribution of modifiable risk/protective factors (cognitive reserve and allostatic load) on specific cognitive domains (episodic memory, executive functions, and attention), taking into account non-modifiable factors [sex, age, and genetic risk for Alzheimer's disease (AD)] and AD-related biomarker amount (amyloid-beta and tau/neuroinflammation) in a healthy late-middle-aged population. One hundred and one healthy participants (59.4 ± 5 years; 68 women) were evaluated for episodic memory, executive and attentional functioning

Indexed as

AD biomarkersallostatic loadAPOEcognitive performancecognitive reservemidlife

Identifiers

PMID34122044
PMCPMC8194490
OpenAlexW3169157112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.