Evidence map›Paper›PMID 34121795›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2020

Excitation-scan Mirror Array System Advancements to Hyperspectral Imaging Applications.

Marina Parker, Craig M Browning, Sam A Mayes, Joshua Deal, Samantha Gunn-Mayes, Thomas C Rich, Silas J Leavesley

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marina ParkerChemical and Biomolecular Engineering, University of South Alabama, AL 36688.
Craig M BrowningChemical and Biomolecular Engineering, University of South Alabama, AL 36688.
Sam A MayesChemical and Biomolecular Engineering, University of South Alabama, AL 36688.
Joshua DealPharmacology, University of South Alabama, AL 36688.
Samantha Gunn-MayesChemical and Biomolecular Engineering, University of South Alabama, AL 36688.
Thomas C RichPharmacology, University of South Alabama, AL 36688.
Silas J LeavesleyChemical and Biomolecular Engineering, University of South Alabama, AL 36688.

Funding

T-type Calcium Channels and von Willebrand Factor ReleaseP01HL066299 · NHLBI · UNIVERSITY OF SOUTH ALABAMA · PI ALVAREZ, DIEGO F. · 2001 to 2022
$34.6M
NHLBI NIH HHS P01 HL066299
6 · The paper itself

Abstract

Hyperspectral imaging (HSI) technology has been applied in a range of fields for target detection and mixture analysis. While its original applications were in remote sensing, modern uses include agriculture, historical document authentications and medicine. HSI has shown great utility in fluorescence microscopy; however, acquisition speeds have been slow due to light losses associated with spectral filtering. We are currently developing a rapid hyperspectral imaging platform for 5-dimensional imaging (RHIP-5D), a confocal imaging system that will allow users to obtain simultaneous measurements of many fluorescent labels. We have previously reported on optical modeling performance of the system. This previous model investigated geometrical capability of designing a multifaceted mirror imaging system as an initial approach to sample light at many wavelengths. The design utilized light-emitting diodes (LEDs) and a multifaceted mirror array to combine light sources into a liquid light guide (LLG). The computational model was constructed using Monte Carlo optical ray software (TracePro, Lambda Research Corp.). Recent results presented here show transmission has increased up to 9% through parametric optimization of each component. Future work will involve system validation using a prototype engineered based on our optimized model. System requirements will be evaluated to determine if potential design changes are needed to improve the system. We will report on spectral resolution to demonstrate feasibility of the RHIP-5D as a promising solution for overcoming current HSI acquisition speed and sensitivity limitations.

Indexed as

CellsFluorescenceHSILEDMicroscopyMoleculesSpectralSpectroscopySystems DesignTissue imagingTransmission

Identifiers

PMID34121795
PMCPMC8191510

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.