Evidence map›Paper›PMID 34121563›Full record

ReviewDrug delivery2021

Recent advances in cell membrane-camouflaged nanoparticles for inflammation therapy.

Rongtao Zhang, Siqiong Wu, Qian Ding, Qingze Fan, Yan Dai, Shiwei Guo, Yun Ye, Chunhong Li, Meiling Zhou

Open access · goldAbstract readReview
In one paragraph

Review in Drug delivery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
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  18. Biomimetic cell membrane-coated poly(lactic-Bioengineering & translational medicine · 2023
    Review
  19. Anti-inflammatory and analgesic effects ofFrontiers in pharmacology · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rongtao ZhangDepartment of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Siqiong WuDepartment of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Qian DingDepartment of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Qingze FanDepartment of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Yan DaiDepartment of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Shiwei GuoDepartment of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Yun YeDepartment of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Chunhong LiDepartment of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, China.
Meiling ZhouDepartment of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Affiliated Hospital of Southwest Medical University · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During inflammation, inflammatory cells are rapidly recruited to sites of infection or injury, where they cross physiological barriers around the infected site and further infiltrate into the tissues. Other cells, such as erythrocytes, endothelial cells and stem cells, also play prominent roles in host defense and tissue repair. In recent years, nanotechnology has been exploited to deliver drugs to sites of inflammation. For example, nanoparticles camouflaged with a cell membrane are a novel drug-delivery platform that can interact with the immune system and that show great potential for treating inflammation. Encapsulating drugs inside plasma membranes derived from various cells involved in inflammatory processes can be effective against inflammation. This review describes the preparation, characterization, and properties of various types of cell membrane-camouflaged biomimetic nanoparticles. It also summarizes preclinical research into their efficacy against inflammation.

Indexed as

Biological MimicryBlood CellsCell MembraneChemistry, PharmaceuticalDrug CarriersDrug StabilityDrug StorageEukaryotic CellsInflammationMacrophagesNanoparticlesParticle SizeProtease InhibitorsStem CellsSurface PropertiesTechnology, PharmaceuticalDrug CarriersProtease InhibitorscamouflagedCell membranedrug deliveryinflammationnanoparticles

Identifiers

PMID34121563
PMCPMC8205088
OpenAlexW3169137329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.